Cancer Early Detection Advanced Research (CEDAR) center is a collaborative institution within the OHSU Knight Cancer Institute. The Knight Cancer Institute, known as one of the pioneers in personalized cancer medicine, is an international leader in research and cancer treatment. At CEDAR our mission is to detect and stop lethal cancers at the earliest stage because early detection saves lives. This is an ambitious goal, one that requires novelty, creativity, and innovation. We are composed of biologists, chemists, biomedical engineers, computationalists, and clinicians conducting groundbreaking translational cancer research to help people maintain a high quality of life and reduce cancer mortality, to create a global early detection community, and to have a positive impact on the Oregon economy.

 

CEDAR is committed to increasing the diversity of the campus community. We at CEDAR are dedicated to promoting inclusion and multiculturalism to build a successful organization by having outstanding researchers of diverse backgrounds work together on multiple projects. We encourage high-risk, high-reward research projects because defeating cancer requires unproven, out-of-the-box thinking. Our research is milestone driven to ensure that each project is fulfilling its stated goals.

 

Every Knight Cancer employee is expected to embody our guiding principles:

• We act BOLDLY—Breakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differently
• We SUPPORT each other—Respect leads to trust, which leads to excellence
• We work as a CONNECTED team—We must leverage our collective brain power to conquer cancer because no one individual can do it alone

As a Computational Biologist, Entry level, you will be a part of collaborative project teams to understand how individual genetic profiles influence risk of cancer development and progression. Specific projects include the Healthy Oregon Project (HOP), which is building a healthy population research repository, and understanding the impact of race on the evolution of mutations in cancer patients. Specific tasks include working with wet-lab researchers to refine methods and protocols to meet project needs, raw data processing, mutation calling, and identification of mutation signatures utilizing existing methods. Additional tasks include metadata cleaning and curation, participation in regular team meetings, publications, and grants.

 

Duties Include:

Data Organization and Management

• Clean and manage metadata
• Access, store, and document raw data
• Coordinate with project team members
• Meet publication requirements, including data and code repositing

Data Analysis

• Sample/sequencing quality control assessment
• Implement existing analytic packages and workflows
• Adapt existing resources as needed to meet project needs
• Develop novel analyses and visualizations

Technical Writing/Communication

• Present at regular team meetings
• Clear code documentation
• Support manuscript preparation
• Support grant writing efforts

• Bachelor's in Computational Biology or related field OR Equivalent combination of training and experience
• Familiar with R, Python, and shell scripting
• Utilize and adapt existing analytic packages and workflows
• Ability to work independently and as part of a team while being collaborative in resolving problems
• Ability to prioritize multiple tasks at one time
• Ability to learn new and innovative processes quickly
• Ability to use tact and diplomacy to maintain effective working relationships

• Bachelor’s degree in (Bio)informatics, or (Bio)statistics, or computer science
• Previous experience managing and processing research data/files
• Familiarity with inherited and acquired variant calling
• Experience with cluster computing
• Understanding evolutionary principles
• Familiarity with SQL

Apply online. Please be sure to upload a Cover Letter and Resume/CV.

Effective Oct. 18, 2021, all OHSU employees were required to be fully vaccinated against COVID-19 unless they had an approved medical or religious exception. If you are hired by OHSU, you will need to provide proof of vaccination (or approved exception) within 10 days of starting work.

 

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Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.