This role is a key position in the laboratory of Dr. Brian O'Roak studying the genetic basis and developmental neuroscience of autism and related disorders.

Key responsibilities will include lab maintenance, supporting studies utilizing, induced pluripotent stem cells (iPSCs), mouse models, as well as human genomics projects. Duties include:

 

• Plans, conducts, and completes laboratory experiments with minimal supervision of the head of the laboratory.  Specific duties will the culture of induced pluripotent stem cells (iPSCs) and other cell types (mainly neuronal).
• Performs primary molecular genetic techniques including PCR, gel electrophoresis, enzymatic analyses, fluorescence assisted cell sorting (FACS), fluorescent and light microscopy, plasmid preparation, DNA isolation from mouse and human tissues, next-generation library preparation, and studies of gene expression.
• Performs complex test procedures and analyses involving multiple procedures and a variety of technical approaches. Operates a variety of instruments and scientific equipment, including operation, quality control and maintenance.  Assists with experiments and assays, preparing solutions, collecting and entering data, maintaining databases, assuring compliance with established safety procedures and maintaining required documentation. Assists with training of students, fellows, and RAs.
• Collects, records, organizes and verifies the accuracy of data. Conducts literature searches and summarizes information in an appropriate format for a particular study; Documents and interprets results of experiments and reports to principal investigator. Presents experimental results at lab meetings and participates in journal and research group meetings. Prepares written reports and, as applicable, regulatory documentation.
• Lab Maintenance: Maintain work and common research areas.
• Logistical Support: Supports PI with management of lab, including, but not limited to, inventory, lab purchase orders, and tracking project related expenditures.

• Bachelor's in relevant field AND 1 years of relevant experience; OR an equivalent combination of training and experience
• Advanced laboratory skills and knowledge of standard molecular biology techniques
• Sterile tissue culture technique
• Proven ability to manage time effectively, especially with competing priorities and high level attention to detail
• Ability to communicate well and work with faculty and staff within the department and University
• Ability to take initiative and work independently and in a team environment
• Ability to complete tasks in an accurate and timely manner

• Master's degree with major courses in the biological sciences
• 3-5 years of experience in an academic research setting, especially with induced pluripotent or neuronal cell culture
• Experience with mouse handling and colony management
• Experience with pluripotent stem cell culture
• Experience with human genetics/genomics

Apply here online. Please be sure to upload a cover letter, resume/CV, and contact information for three references. 

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.


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