Oregon Health & Science University

Computational Biologist 1-2

Job Locations US-OR-Portland
Requisition ID
Position Category
Position Type
Regular Full-Time
Job Type
CEDAR - Knight Cancer Institute
Salary Range
Range minimum: $58,000 CB1, $70,100 CB2/year. Starting salary will be determined based on education, experience, and internal equity at the time of offer
Monday through Friday
8:30am to 5:00pm plus occasional nights and weekends

Department Overview

The Cancer Early Detection Advanced Research (CEDAR) center is a collaborative institution within the OHSU Knight Cancer Institute. The Knight Cancer Institute, known as one of the pioneers in personalized cancer medicine, is an international leader in research and cancer treatment. At CEDAR our mission is to detect and stop lethal cancers at the earliest stage because early detection saves lives. This is an ambitious goal, one that requires novelty, creativity, and innovation. We are comprised of biologists, chemists, biomedical engineers, computationalists, and clinicians conducting groundbreaking translational cancer research to help people maintain a high quality of life and reduce cancer mortality, to create a global early detection community, and to have a positive impact on the Oregon economy.  


Our Commitment to Diversity: CEDAR is committed to increasing the diversity of the campus community. We are dedicated to promoting inclusion and multiculturalism by having outstanding researchers of diverse backgrounds work together on multiple projects. We encourage high-risk, high-reward research projects because defeating cancer requires out-of-the-box thinking and new perspectives. Our research is milestone driven to ensure that each project is fulfilling its stated goals. 


Every Knight Cancer employee is expected to embody our guiding principles

  • We act BOLDLY—Breakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differently
  • We SUPPORT each other—Respect leads to trust, which leads to excellence
  • We work as a CONNECTED team—We must leverage our collective brain power to conquer cancer because no one individual can do it alone

Function/Duties of Position

The Knight Cancer Institute Cancer Early Detection Advanced Research Center (CEDAR) at Oregon Health & Science University seeks an experienced Computational Biologist who will leverage existing tools and develop custom computational methods to analyze single-cell multi-omic datasets.


In this role you will work on research project teams that include CEDAR faculty such as Gurkan Yardimci and Ted Braun, and others over time. The projects involve the use of single-cell technologies to understand the role of chromatin regulation in the cellular progression from a normal to a cancer phenotype. In particular, we are interested in understanding how hematopoietic stem cells acquire mutations and shift from a normal to a pathologic phenotype.

Required Qualifications

  • Master's Degree in Computational Biology or related field AND 3 years of relevant experience OR Bachelor's Degree in Computational Biology or related field AND 6 years of relevant experience
  • Those with Master's Degree in Computational Biology or related field OR Bachelor's Degree in Computational Biology or related field AND 3 years of relevant experience will be considered at the Comp Bio 1 level
  • 3+ years of relevant experience as a computational biologist, bioinformatician, biostatisticial, cheminformatician or other data science analyst or biological researcher
  • Demonstrated excellence in research related to genomic analysis, machine learning, or image analysis, including experience with next-gen sequencing or medical imaging
  • Advanced skills in a high level programming language, preferably Python or R, preferably in Linux or Unix, optionally with Java or C/C++
  • An understanding of machine learning, data modeling or statistical techniques, such as mixed-model regression, principal component analysis, classifier construction and validation, biomarker discovery and optimization methods
  • Experience using structured engineering methods for specifying, designing, and implementing systems
  • Experience with architecture and tools for managing “omics” data OR imaging data
  • Ability to prioritize multiple tasks at one time
  • Excellent communication, analytical and organizational skills:  both written and verbal
  • Ability to work independently and as part of a team while being collaborative in resolving problems
  • Intermediate skills with Microsoft Office (Excel, Outlook, Access, Word, and PowerPoint) on Window OS. Ability to accurately type 60wpm
  • Must possess energy and drive to coordinate multiple projects simultaneously
  • Ability to use tact and diplomacy to maintain effective working relationships

Preferred Qualifications

  • 2+ years team science experience in a collaborative research environment
  • 1+ year of hands-on experience with generation and analysis of omic or imaging data
  • High performance computing experience
  • A passion for open-access innovation

Additional Details

Apply online. Please be sure to upload a Cover Letter and Resume/CV.


Effective Oct. 18, 2021, all OHSU employees were required to be fully vaccinated against COVID-19 unless they had an approved medical or religious exception. If you are hired by OHSU, you will need to be fully vaccinated (or obtain an approved exception) prior to starting work, and need to provide proof of vaccination (or approved exception) within 10 days of starting work.


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All are welcome

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.

As an organization devoted to the health and well-being of people in Oregon and beyond, OHSU requires its employees to be fully vaccinated against COVID-19.


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