The research laboratory of Professor Andrew Emili pursues collaborative multi-disciplinary systems biology projects within the OHSU Knight Cancer Institute. The Knight Cancer Institute, known as one of the pioneers in personalized cancer medicine, is an international leader in research and cancer treatment. This is an ambitious group, one that requires novelty, creativity, and innovation. We are composed of experimental biologists, protein biochemists, analytical chemists, biomedical engineers, and computationalists conducting groundbreaking research to understand disease mechanisms and identify novel drug targets, to ultimately help people maintain a high quality of life and reduce cancer mortality, while creating a broader systems biology research community.
Every Knight Cancer member is expected to embody our guiding principles:
The Emili laboratory is currently seeking applicants to fill multiple postdoctoral positions. The lab offers a unique opportunity for outstanding, driven, and creative postdoctoral fellows to perform cutting edge proteomics research, ranging from understanding basic cancer biology to developing novel technologies to aid disease detection and drug development. The Emili laboratory is dedicated to promoting inclusion and multiculturalism to build a successful team by having outstanding researchers of diverse backgrounds work together on multiple projects. We encourage high-risk, high-reward research projects because defeating cancer requires innovation and out-of-the-box thinking.
As a Post-Doctoral Fellow, you will support mass spectrometry-focused proteomics studies within the Emili network systems biology laboratory, a new leading faculty member of the Knight Cancer Institute at Oregon Health and Science University. Major projects involve interrogation of animal model and primary patient specimens, primarily but not limited to biopsies, tissue specimens and cultured cells, to identify and validate biological systems, protein complexes and biochemical pathways altered in across multiple cancer indications and to support examination of biological mechanisms of action. The major role for the candidate will be to serve as an experimentalist and a proteomic mass spectrometry data generator. This role will involve executing a number of research projects throughout their lifespan including providing significant input on experimental study design, control inclusion and placement, data acquisition strategies and, critically, analysis and mining of the resulting datasets. Additional and important roles for the candidate will involve performing sample acquisition and processing, instrument optimization, data acquisition, and organized tracking of samples, datasets, and relevant methods (both experimental and analytic) for summary scientific reports, presentations and eventual publications. The candidate will be required to explore and apply advanced LC/MS-based proteomic capabilities, including affinity-labeling/capture, quantitative and integrative-analyses, and will need to scale analytic platforms and algorithms for larger-scale studies. The candidate should operate effectively with internal team members and actively solicit input from expert external analytic consultants and collaborators. The candidate will likely be required to oversee more junior analysts and experimental researchers and train them on methods and approaches to build redundancy of expertise as much as possible. The candidate will demonstrate the ability to independently design, execute and interpret proteomic method development studies critical to the evolution of our workflows to support early detection and other clinical sample interrogation.
Apply online. Please be sure to upload a Cover Letter and Resume/CV.
Effective Oct. 18, 2021, all OHSU employees were required to be fully vaccinated against COVID-19 unless they had an approved medical or religious exception. If you are hired by OHSU, you will need to provide proof of vaccination (or approved exception) within 10 days of starting work.
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