Oregon Health & Science University

Associate Core Scientist

Job Locations US-OR-Portland
Requisition ID
Position Category
Position Type
Regular Full-Time
Job Type
University Shared Resources
Salary Range
$57,969 - $86,832 Commensurate with qualifications, experience and internal equity
Monday - Friday
8:00 am - 5:00 pm with occasional nights and weekends
HR Mission
Drug Testable

Department Overview

OHSU is currently seeking to hire an Associate Core Scientist who is talented, motivated, and highly interactive to work in a multidisciplinary team as part of the Multiscale Microscopy Core (MMC)! The MMC is a state-of-the-art electron microscopy core that provides imaging services, technical support and training to academic and corporate users. Included at OHSU’s Electron Microscopy Core are two Transmission Electron Microscopes (TEM), a Tecnai T12 Biotwin, and a Glacios cryoTEM microscope (outfitted with a K3 direct electron detector). This facility also has a Helios G3 FIB-SEM, a newly installed Helios UC5 FIB-SEM equipped with Oxford EDS detector and Leica cryo stage, a Apreo SBF-SEM and a CorrSight for correlative light and EM projects.


The Core Scientist family provides technology expertise for researchers across campus. Core Scientists are involved with providing service functions that include service projects, assay services, or equipment training. Additional duties include quality assurance and compliance, project and request tracking. Core leadership duties includes training, and mentoring junior staff. 

Function/Duties of Position

The Associate Core Scientist will provide support to the MMC’s activities and core director by communicating with core facility users, providing sample preparation, imaging acquisition and training to new users and junior staff. This position will also be involved in laboratory maintenance including consumables and reagents restocking, operations with advanced electron microscope equipment (TEM, cryoTEM, SEM, FIB-SEM and SBF-SEM), and assisting with the organization of laboratory events, which includes training and workshops. Additionally, this role will provide administrative support of laboratory operations including iLabs, ordering, maintenance of records and inventory databases and liaising with the manufacturers and vendors for purchases, repairs, upgrades and application support. 


The successful candidate for this position will have experience working in a service center where they have assisted in maintaining a smooth and efficient working environment providing services to internal and external users. Ideally, candidates will have a high level of professional expertise through familiarity with current scientific literature and have experience developing new workflows, protocols, as well as training and supporting novice users. This position requires the ability to work both independently and within a team, it is also important candidates have strong communication skills with the ability to prioritize multiple tasks, projects, and competing deadlines to accomplish research goals.

This position will perform work in a laboratory setting, with potential risk of exposure to chemicals and gases (liquid nitrogen). The successful candidate will follow safety regulations, lab compliance protocols, and have the ability to wear personal protective equipment when necessary. Additional safety training will be required to work with cell lines/infectious bacteria or viruses and working within a BSL-2 environment.


This position is located in the Robertson Life Science Building on OHSU’s South Waterfront campus; work hours are Monday – Friday, 8:00am – 5:00pm with occasional evening and weekend work as needed.

Required Qualifications

  • Master's Degree in relevant field AND 3 years of relevant experience or core-relevant expertise; OR 
  • Bachelor's with relevant coursework AND 5 years of relevant experience or core-relevant expertise.
  • Skilled in operating Transmission EM (Room temperature and cryo) and Scanning EM.
  • Basic knowledge on FIB-SEM and SBF-SEM to acquire 3D datasets.
  • Skilled in ultramicrotomy and can train novice user.
  • Skilled in EM sample preparation techniques (room temperature and cryo).

Preferred Qualifications

  • Image processing for SPA.
  • Demonstrated ability to set up automated data acquisition for single particle studies.
  • Tomography data collection and reconstruction.
  • Knowledge in Tokuyasu sectioning and high-pressure freezing techniques.
  • Previous experience using cryo-EM, and direct electron detectors.
  • Experience managing expensive instrumentation. 

Additional Details

  • Please be sure to upload a cover letter, CV/resume, and 3 professional references who can speak to your experiences and abilities.


    OHSU offers a generous benefits package that includes:

    • Vacation - up to 208 hours per year pending length of service for full-time employees
    • Sick Leave - 64 hours per year for full-time employees
    • 10 paid holidays per year
    • Comprehensive medical, dental & vision care plans. Covered 100% for full-time employees and 88% for dependents
    • $25K of term life insurance provided at no cost to the employee
    • Retirement: Choose between pension plan or employee matching voluntary savings plan
    • Substantial Tri-met and C-Tran discounts
    • Tuition Reimbursement 
    • OHSU is a non-profit organization, so we qualify for the Public Loan Forgiveness Program
    • Innovative Employee Assistance Program (EAP)
    • Health Care and Dependent Care Flexible Spending Accounts
    • Employee Discounts

All are welcome

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.

As an organization devoted to the health and well-being of people in Oregon and beyond, OHSU requires its employees to be fully vaccinated against COVID-19.


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