The Vaccine and Gene Therapy Institute (VGTI) at Oregon Health & Science University (OHSU) has assembled a multidisciplinary team of scientists to respond to serious viral disease threats, including AIDS, chronic viral infection-associated diseases, newly emerging viral diseases and infectious diseases of the elderly. Our programs are intended to span the continuum between basic and clinical science, in which discoveries are rapidly advanced from the level of molecular and cellular biology through animal models and ultimately into clinical testing. The development of this unique program in immunology and virology provides an important training opportunity for graduate students and postdoctoral fellows at OHSU. This is why an important part of our mission is the training of young scientists in newer academic disciplines emerging at the Vaccine and Gene Therapy Institute.

Uncontrolled inflammation generates significant morbidity and mortality in many diseases of infectious (e.g. HIV, Mtb) and non-infectious (e.g. inflammatory bowel disease) origin. By utilizing a variety of non-human primate models of human diseases, the Estes Laboratory works to elucidate determinants of local and systemic inflammation leading to tissue pathology, disease progression, and pathogen persistence, as well as test therapeutics to modulate the immune landscape, restore immune homeostasis, and reduce pathogen tissue reservoirs.  

 

The Estes Lab is currently recruiting a highly self-motivated and energetic postdoctoral researcher to lead a project within the new multi-center Cascade IMPAc-TB consortium, an ambitious NIH contract designed to accelerate progress in tuberculosis vaccine development. In collaboration with the Gerner Lab in Seattle, this project is designed to provide a spatial framework, via advanced in situ hybridization and immunofluorescent techniques, that will complement and synergize with other consortium projects. Additionally, this individual will also lead and collaborate on other projects within the lab, including projects to understand HIV/SIV reservoir dynamics. Background in a relevant immunology lab is required. Direct experience working on TB, HIV/SIV, non-human primate models, multiplexed in situ hybridization and protein immunofluorescence, and/or multispectral imaging is highly desirable.

 

Please note that this position is at OHSU's West Campus (Beaverton). Submit a resume, cover letter, and at least three references to be considered for this position.

• Ph.D. in immunology, microbiology, virology, or closely related field
• Research experience with in vivo models of TB, HIV, SIV, non-human primates, advanced microscopy, multi-spectral imaging, or closely related areas.
• Must be a team player, have excellent oral and written communication skills, willing to work with non-human primate and/or biohazardous samples, and comfortable using computers (Mac, PC), databases, and advanced software programs.

• First-author publications involving the immunology or pathology of TB, HIV, SIV, non-human primates, advanced microscopy, or multi-spectral imaging.
• Experience with animal research, especially non-human primates, image analysis experience, and Python programing.

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.


As an organization devoted to the health and well-being of people in Oregon and beyond, OHSU requires its employees to be fully vaccinated against COVID-19.