We, at the Knight Cancer Institute, are driven to cure cancer.

 

So, if you’re innately inquisitive, motivated, and truly want to explore novel opportunities that seek to make a real difference in the way we treat cancer, then this position may be right for you.

We are seeking a Research Associate to work at the intersection of biomedical data science and cancer metabolic reprograming that occur during cancer treatment, as part of the Thomas Lab. Specifically, we seek to identify metabolic vulnerabilities that occur under selective pressure of treatment, which can then be exploited to eliminate tumor cells.

Previous publications from our group include: Genes & Development 20, 2067-2084; Metabolites 5, 82; Cell 174: 758-769; Nature Medicine 12,122-127; Cancer Journal 15, 406-420; Science Translational Medicine 3(85): 85ra47; J Clin Oncol 36: 2492-2503; Cell Rep Med 2, 100267.

You will be creative and driven; able to analyze and apply computational tools to emerging genomic technologies to address basic and translational questions in our research area, including cancer metabolism, cancer therapeutics and biomarker discovery. Important findings will be further explored experimentally, both in our lab and through collaboration, with the ultimate goal of translating promising findings into clinical trials. You should be  highly-motivated with a basic background in molecular/cellular biology and have a strong desire to learn and integrate biological and computational modeling techniques. Computer programming skills (Python, R) will be highly advantageous.

 

You will be a highly motivated candidate with a background in molecular/cellular biology and/or genetics, who will be responsible for independently and collaboratively performing experiments in the laboratory which will include DNA, RNA, Protein, Western blotting, Q-Real Time PCR, Tissue culture, Transfections, Flow Cytometry, Imaging, working with mice, developing and maintaining patient derived organoids, and then carry out data analysis resulting from experiments. You will be responsible for developing single cell genomics and analyses. Analytical expertise in Excel, Graph Pad Prism, Calcusyn is required.

 

Position requires strong attention to detail, ability to design, perform experiments and analyze data independently, multi-tasking, working as part of a team and willingness to learn new technologies. 

 

Lab management duties to include ordering supplies, arranging equipment maintenance and ensuring smooth workflows in the lab. Occasional evening and weekend work is required

Education and experience:

 

Master's Degree in relevant field AND 3 years of relevant experience OR
Bachelor's Degree in relevant field AND 5 years of relevant experience.

 

Key Competencies required: 

• Highly motivated and committed to academic biomedical research
• Overall, effective judgment and problem solving will little or no supervision is imperative in all facets of this position
• Analytical expertise in Excel, Graph Pad Prism, Calcusyn 
• Strong attention to detail
• Ability to perform experiments and analyze data independently
• Ability to work as part of a team and willingness to learn new technologies.
• Highly motivated and committed to academic biomedical research
• Experience with animal (mouse) work
• Ability to prioritize multiple tasks at one time
• Excellent communication, analytical and organizational skills: both written and verbal
• Proficiency with computers running Windows and PC applications e.g. MS Excel, Oracle, Access, Word and PowerPoint.
• Ability to use tact and diplomacy to maintain effective working relationships

Onsite work in a laboratory is required. Must be able to travel to all Knight worksite locations. Occasional evening and weekend work may be necessary.

• PhD degree in Cell Biology / Molecular Biology/Genetics
• Bioinformatic experience (R, Python)

OHSU offers a generous benefits package that includes:

• Vacation - up to 208 hours per year pending length of service for full-time employees
• Sick Leave - 64 hours per year for full-time employees
• 10 paid holidays per year
• Comprehensive medical, dental & vision care plans. Covered 100% for full-time employees and 88% for dependents
• $25K of term life insurance provided at no cost to the employee
• Retirement: Choose between pension plan or employee matching voluntary savings plan
• Substantial Tri-met and C-Tran discounts
• Tuition Reimbursement
• OHSU is a non-profit organization, so we qualify for the Public Loan Forgiveness Program
• Innovative Employee Assistance Program (EAP)
• Health Care and Dependent Care Flexible Spending Accounts
• Employee Discounts

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Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.


As an organization devoted to the health and well-being of people in Oregon and beyond, OHSU requires its employees to be fully vaccinated against COVID-19.