Overview: The Cancer Early Detection Advanced Research (CEDAR) center is a collaborative institution within the OHSU Knight Cancer Institute. The Knight Cancer Institute, known as one of the pioneers in personalized cancer medicine, is an international leader in research and cancer treatment. At CEDAR our mission is to detect and stop lethal cancers at the earliest stage because early detection saves lives. This is an ambitious goal, one that requires novelty, creativity, and innovation. We are comprised of biologists, chemists, biomedical engineers, computationalists, and clinicians conducting groundbreaking translational cancer research to help people maintain a high quality of life and reduce cancer mortality, to create a global early detection community, and to have a positive impact on the Oregon economy.

 

Our Commitment to Diversity: CEDAR is committed to increasing the diversity of the campus community. We are dedicated to promoting inclusion and multiculturalism by having outstanding researchers of diverse backgrounds work together on multiple projects. We encourage high-risk, high-reward research projects because defeating cancer requires out-of-the-box thinking and new perspectives. Our research is milestone driven to ensure that each project is fulfilling its stated goals.

 

 

Every Knight Cancer employee is expected to embody our guiding principles:

• We act BOLDLY—Breakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differently
• We SUPPORT each other—Respect leads to trust, which leads to excellence
• We work as a CONNECTED team—We must leverage our collective brain power to conquer cancer because no one individual can do it alone

As a Senior Research Assistant, you will be part of collaborative project teams focusing on advancing early cancer detection. You will support CEDAR research by maintaining CEDAR laboratories and supplies and assisting in research activities. Senior Research Assistants are assigned to program projects as needed.   The successful candidate must be highly motivated, adaptable and experienced in all aspects of the research laboratory. You will have a detailed knowledge of all aspects of laboratory research, and you must work independently in designing and implementing experiments for research projects, exhibiting exceptional organizational and communication skills, and training other team members (e.g., research assistants and students) as needed. The successful candidate will work closely with Jungsun Kim and other CEDAR members to support investigating the role of HBP1 transcription factor regulation in the pancreatic cancer model. In addition, the responsibilities will include leading a team on a full CEDAR project, instructing them on how to support biology experiments and assisting in experimental design.

 

Duties include but not limited to:

Laboratory research:

• Applies molecular biology techniques, including chromatin precipitation, western blot, recombinant nucleic acids, human biopsy samples, and wild-type and recombinant viruses such as retroviruses, adenovirus and Sendai virus
• Conducts mammalian cell culture and animal experiments in lab; prepare and validate tissue culture media, and operate a variety of instruments and equipment, including flow cytometry and immunofluorescence microscopy, and keep records of cell line stocks and laboratory reagents
• Ability to conduct with high quality all aspects of mammalian cell culture using established SOPs, including culture initiation, propagation, cell line validation, testing for pathogens, and cryopreservation of cells, including primary human cells
• Participate in some design of experiments or research studies and procedures

Laboratory Organization and Compliance

Additional duties as assigned by project leader or laboratory manager

Lab Support

• Bachelor's in relevant field AND 1 years of relevant experience OR Equivalent combination of training and experience
• Relevant experience in cancer biology or biochemistry/molecular biology lab after final degree
• Proficient in mammalian cell culture

• Biochemistry and molecular biology skills (e.g., co-immunoprecipitation, western blot, chromatin precipitation)
• Animal in vivo work
• Genome editing
• Stem cell culture
• Flow cytometry
• Organoid culture

Apply online. Please be sure to upload a Cover Letter and Resume/CV.

Effective Oct. 18, 2021, all OHSU employees were required to be fully vaccinated against COVID-19 unless they had an approved medical or religious exception. If you are hired by OHSU, you will need to provide proof of vaccination (or approved exception) within 10 days of starting work.

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Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.


As an organization devoted to the health and well-being of people in Oregon and beyond, OHSU requires its employees to be fully vaccinated against COVID-19.