The Mishra lab aims to unravel the mechanisms underlying the neurovascular dysfunction in neurological conditions, with particular focus on ischemic injury and their contributions to Alzheimer’s disease and related dementias. Current projects in the lab aim to characterize the neuroinflammatory processes, especially the responses of astrocytes and microglia, following mild ischemia that may accelerate pathology in Alzheimer’s disease (AD) and understand the mechanistic cellular and molecular pathways by which this leads to neurovascular dysfunction. Two fully-funded postdoctoral research positions are open to lead studies along these lines:
The successful candidates will be responsible for experimental design, data collection and analysis, reading the pertinent literature, writing manuscripts for publication, and generally leading the project under the guidance of the PI.
The post-doc will also facilitate lab organization, participate in lab meetings, attend research seminars and journal clubs, present their work at national/international conferences, and help supervise research assistants and early graduate students in the lab.
Experience in mouse genetics, animal surgery, immunohistochemistry and western blotting, in vivo 2 photon or MRI imaging, and behavioral assessment are the main criteria. A willingness to learn and passion for scientific inquiry are a must!
Ideally, the candidate would be able to start in the lab in the fall or winter of 2023.
Experience with:
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