The OHSU Knight Cancer Institute is a pioneer in personalized cancer treatment and research. The institute focuses on precision oncology, the early detection, prevention, and treatment of cancer, and creating a welcoming and supportive environment for its caregivers, researchers, and support personnel. Knight affiliates subscribe to three guiding principles: we are bold, we are supportive, and we work as a connected team in our fight to end cancer as we know it.  We’d love for you to join us!

 

The Moran lab is working to understand how sex hormones influence the immune system and how we can use this knowledge to develop better cancer treatments. We have exciting projects combining cancer biology and immunology, and work in a collaborative environment with many fantastic scientists and clinicians. Dr. Moran is looking for a Senior Research Assistant to provide technical and scientific expertise in computational biology, immunology, and cancer biology. Dr. Moran aims to foster a friendly and inclusive work environment with collaborative goal-setting and problem-solving opportunities.

 

Work in the Moran Lab will be focused on a combination of wet and dry bench research involving small animals, including surgery, necropsy and animal tissue processing, large data analysis and integration with wet bench observations. Wet bench duties include working with rodents, flow cytometry, basic immunohistochemistry, basic cellular and molecular procedures, processing of human tissue, molecular biology and biochemistry assays. Dry bench duties will include ‘omics data analysis, organization, and discovery using an array of software platforms including but not limited to GitHub, Ensembl, Seurat, DESeq2, FastQC, etc. Candidate must be experienced in working within a team, demonstrate a willingness for collaboration, have data management experience, have large data processing, quality control, and analysis expertise, and demonstrate a willingness to learn.  Ultimately, this position directly supports the principle investigators’ discoveries and scholarly work.

• Wet lab duties:
  • Assist researchers with handling, harvesting and/or processing animal tissues, organizing materials and the lab environment.
  • Basic cellular and molecular techniques.
  • Basic immunohistochemistry.
  • Use of aseptic technique.
  • Training and mentoring responsibilities will also be required periodically.
  • Assist researchers with designing and running flow cytometry panels, using animals’ cells and tissues.
  • Experience with FlowJo would be helpful.
  • Manipulating flow cytometry data and generating graphs.
• Dry lab duties:
  • Use of RStudio, Ensembl, Seurat, DESeq2, GitHub, and other data analysis software tools to analyze various epigenetic, genetic, and transcriptomic datasets.
  • Data acquisition, organization, quality control, metadata collection and analysis, data deposit and interfacing with computational colleagues will be required. Proficiency in Python and R and the ability to teach others in the lab.

• Bachelor's in relevant field AND  1 years of relevant experience OR 
• Equivalent combination of training and experience
• 1 year of computational experience; working knowledge of R, Python, Seurat, biostatistics, etc.

• Master’s degree

• Prefer 1 year of relevant experience, including hands-on experience with animal handling and basic molecular experimental techniques.

• One year experience with the following,

  • Flow cytometry
  • Basic cellular and molecular experimental techniques.
  • Understanding of basic statistics and some of its applications to biomedical science. 
  • Ability to prioritize multiple tasks at one time. 
  • Knowledge and understanding of computational platforms.
  • Working knowledge of Python, R,
• Excellent communication, analytical and organizational skills, both written and verbal. 
• 2 years experience with the following,
  • experience in a professional, team-oriented biology environment.
  • Animal handling and experimentation.
  • Flow cytometry experience.
  • Immunohistochemistry
  • Knowledge and understanding of computational platforms.
  • Working knowledge of Python, R,

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.