Overview: The Cancer Early Detection Advanced Research (CEDAR) center is a collaborative institution within the OHSU Knight Cancer Institute. The Knight Cancer Institute, known as one of the pioneers in personalized cancer medicine, is an international leader in research and cancer treatment. At CEDAR our mission is to detect and stop lethal cancers at the earliest stage because early detection saves lives. This is an ambitious goal, one that requires novelty, creativity, and innovation. We are comprised of biologists, chemists, biomedical engineers, computationalists, and clinicians conducting groundbreaking translational cancer research to help people maintain a high quality of life and reduce cancer mortality, to create a global early detection community, and to have a positive impact on the Oregon economy.
Our Commitment to Diversity: CEDAR is committed to increasing the diversity of the campus community. We are dedicated to promoting inclusion and multiculturalism by having outstanding researchers of diverse backgrounds work together on multiple projects. We encourage high-risk, high-reward research projects because defeating cancer requires out-of-the-box thinking and new perspectives. Our research is milestone driven to ensure that each project is fulfilling its stated goals.
Every Knight Cancer employee is expected to embody our guiding principles:
CEDAR is hiring a talented, motivated and highly interactive Senior Research Associate to participate in our growing electron microscopy (EM) research portfolio. You will use and expand on existing imaging pipelines—from sample preparation, to imaging, to post-processing of 2- and 3-dimensional light and electron microscopy datasets—to identify changes in cellular signaling networks that accompany cancer progression and drug resistance in model systems and clinical specimens.
A background in high-resolution EM is necessary, in particular, Scanning Electron Microscopy (SEM), Focused Ion Beam (FIB-SEM) and Transmission Electron Microscopy (TEM). Development and innovation of multi-modal imaging techniques and analyses, i.e. correlative light and electron microscopy (CLEM), will be a central theme of projects. You will be working closely with an interdisciplinary team of biologists, engineers, microscopy experts, and computer scientists to characterize model cancer systems, clinical specimens, “lab-on-a chip” devices, and novel biotechnology using traditional 2D EM and volume EM.
This position requires comfort using commercially available software (Amira, Dragonfly, ImageJ, WebKnosses, Napari) and custom-built, deep-learning based software packages to help enable the large-scale image analysis of large EM datasets. Wet lab experience with respect to handling biological specimens and hazardous chemicals is needed. Experience with Python and knowledge of additional imaging modalities, such as confocal, light sheet, multiplexed immunofluorescence and super resolution fluorescence microscopy would be a bonus.
Applicants without a demonstrated track record of professional research outputs post-doctoral degree will be considered at the Research Associate level.
Education & experience:
Knowledge, skills, and abilities:
Apply online. Please be sure to upload a Cover Letter and Resume/CV.
We offer a variety of benefits on top of joining a thriving organization:
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