The Thomas lab focuses on understanding the role of CD8 memory T cells as critical regulators of immune tolerance in the human gastrointestinal tract and liver. To better understand the contribution of CD8 tissue-resident memory T cells to tolerance in digestive organs, we study their function and heterogeneity both in healthy individuals and across a variety of inflammatory conditions including drug-induced gastrointestinal toxicities (i.e. checkpoint inhibitor associated colitis and hepatitis) and spontaneous autoimmune diseases (i.e. inflammatory bowel disease, microscopic colitis, celiac disease).

 

We are seeking a motivated Postdoctoral Fellow to conduct research in human gastrointestinal mucosal immunology in both healthy individuals and those with colitis that arises in the context of immune checkpoint inhibitors and spontaneous autoimmune disease. Specific projects will be determined by the applicant’s skill set and articulated research interests, though may include research in the areas of mucosal immunology focused on understanding the tissue spatial organization of immune responses, identifying immune cell subsets and their mediators in human digestive organs, and identifying epigenetic mediators of inflammation in the gastrointestinal tract. Experience in immunology and ex vivo tissue culture-based assays are a requisite.

 

The Postdoctoral Fellow will be the primary strategist in scientific aspects of the assigned project and may participate in supervision of some activities of research assistants, including taking responsibility for expensive equipment and experimental design. It is expected that the Postdoctoral Fellow will write scientific papers and abstracts, submit manuscripts for publication, and seek out and apply for grants and additional funding to support this research.

 

Curriculum vitae (CV), one-page research description with relevant publications and career goals, and names/contact information for at least three professional references should be uploaded with the application

 

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud to be an equal opportunity, affirmative action organization. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. Applicants with disabilities can request reasonable accommodation by contacting the Affirmative Action and Equal Opportunity Department at 503-494-5148.

• Preforming laboratory research; conducting experiments; Collecting, analyzing, and quantifying data; Assisting in planning and designing standard research operations.
• Preparation of reports, manuscripts and peer reviewed journals for publication. Submit applications for grant funding in support of this research.
• Presenting research at lab meetings, seminars and conferences. 

• PhD in related field of research

• 3+ years prior life sciences laboratory experience (may be completed as part of graduate education)

• Experience in immunology and basic cell biology techniques is a requisite

• PhD in Immunology 

• 5+ years of laboratory research (may be completed as part of graduate education)

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.