The OHSU Knight Cancer Institute, known as one of the pioneers in personalized cancer medicine, is an international leader in research and cancer treatment. Driven by its mission to end cancer as we know it, the institute is building upon its expertise in targeted treatments to advance the early detection of cancer when the disease is most treatable.

 

The Division of Oncological Science is a collaborative and multidisciplinary division with a broad range of expertise and well-established research programs in the following four disciplines: cancer system biology, medicinal medicine, cancer data science, and cancer population science. There are opportunities for interaction with physicians and pharmaceutical collaborators.

 

Every Knight Cancer employee is expected to embody our guiding principles: 

• We act BOLDLY—Breakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differently
• We SUPPORT each other—Respect leads to trust, which leads to excellence
• We work as a CONNECTED team—We must leverage our collective brain power to conquer cancer because no one individual can do it alone

A postdoc position is available for a motivated candidate to join the Zhang laboratory in the Division of Oncological Science within the Knight Cancer Institute at OHSU. The postdoc will be co-mentored by Dr. Gordon Mills, a nationally recognized leader in precision oncology and cancer systems biology, currently serving as the Director of Precision Oncology, SMMART, and AMTEC clinical trials at the Knight Cancer Institute.

 

This position will assist in research that shows how temporal, spatial, and dose perturbation of oncogenes and tumor suppressor genes predispose to cancer development and how could we use the specific vulnerabilities, including the haploinsufficient phenotype observed in patients with chromosome and copy number deletions to develop synthesize lethal therapeutics. The selected candidate will help establish project goals, define short- and long-term scientific strategies, perform in vitro and in vivo experiments, and contribute to the preparation of project-related documents, including presentations, grant applications, and publications.

• Maintain long-term tissue cultures and mouse colonies for experimental purposes.
• Plan and perform experiments related to the project's research goals, including in vitro and in vivo experiments: molecular and cellular biology assays, flow cytometry, mammalian cell culture, biochemistry assays, utilization of in-vivo models and associated techniques, cell isolation and DNA/RNA purification from bacterial cultures, mammalian cell cultures, in-vivo models, and patient samples.
• Writing manuscripts and grants
• Inventory, lab organization, and maintenance
• Collect, record, organize, and analyze data
• Read literature, data, and figure preparation, attend and present at lab meetings

Education & experience:

• PhD or MD in relevant filed
• Experience with a transgenic mouse model and/or bone marrow transplantation model
• Experience in FACS-based methods, biochemistry, and molecular biology

Knowledge, skills, and abilities:

• Strong background and training in cell/cancer biology science and experimental techniques
• Strong writing and editing skills
• Ability to work independently, plan long-term and short-term research strategies and experiments
• Ability to prioritize multiple tasks at one time and be task-oriented and flexible with working schedule
• Demonstrated ability to learn new and innovative processes quickly
• Demonstrate literature searching and critical analysis skills
• Demonstrate a high degree of responsibility 

• First-authored publications in relevant research areas
• Experience in using R or other computational Data analytics methods.
• Experience with transgenic mice, multicolor flow cytometry staining, and flow data analysis skills

Apply online. Please be sure to upload a Cover Letter and Resume/CV.

 

We offer a variety of benefits on top of joining a thriving organization:

• Medical, dental and vision coverage at no or low cost to employees
  • Covered 100% for full-time employees and 88% for dependents
• Several retirement plans to choose from with contributions from OHSU
• 120 hours of vacation time per year
• 96 hours of sick leave a year (prorated for part-time employees)
• Commuter subsidies
• Tuition reimbursement
• Access to group life insurance, disability insurance and other supplemental benefits
• Annual Raises
• Growth/Development Opportunities
• Employee discounts to local and major businesses

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Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.