The OHSU Knight Cancer Institute, known as one of the pioneers in personalized cancer medicine, is an international leader in research and cancer treatment. Driven by its mission to end cancer as we know it, the institute is building upon its expertise in targeted treatments to advance the early detection of cancer when the disease is most treatable.

 

The Cancer Early Detection Advanced Research (CEDAR) Center, a collaborative institution within the OHSU Knight Cancer Institute, is dedicated to pioneering new methods for early cancer detection. The Knight Cancer Institute, recognized globally for its leadership in personalized cancer medicine, continues to advance the frontiers of research and treatment. At CEDAR, our mission is to detect and stop lethal cancers at their earliest stages because early detection saves lives.

 

In this dynamic and inspiring environment, the research group led by Dr. Hisham Mohammed is seeking a talented Computational Biologist with a strong focus on DNA methylation data analysis. The successful candidate will play a critical role in analyzing large-scale DNA methylation datasets, including both bulk sequencing and single-cell data, with the goal of longitudinally generating disease-specific "clocks" for early cancer detection.

 

Every Knight Cancer employee is expected to embody our guiding principles: 

• We act BOLDLY—Breakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differently
• We SUPPORT each other—Respect leads to trust, which leads to excellence
• We work as a CONNECTED team—We must leverage our collective brain power to conquer cancer because no one individual can do it alone

Key Responsibilities:

• Process, analyze, and interpret large-scale DNA methylation datasets, including bulk and single-cell sequencing data.
• Apply existing bioinformatics tools and methods for DNA methylation analysis while also developing novel approaches as necessary to address specific research questions.
• Generate disease-specific epigenetic "clocks" through longitudinal data analysis to enhance our understanding of cancer progression and early detection.
• Collaborate with a multidisciplinary team to integrate DNA methylation data with other omics data, contributing to a holistic understanding of cancer biology.
• Stay current with advances in computational biology, DNA methylation research, and multi-omics analysis, continuously adapting and applying new techniques to ongoing research.

Education & experience:

Compuatational Biologist 1

• Master's Degree in Computational Biology or related field OR
• Bachelor's Degree in Computational Biology or related field AND 3 years of relevant experience

Compuatational Biologist 2

• Master's Degree in Computational Biology or related field AND 3 years of relevant experience OR

• Bachelor's Degree in Computational Biology or related field AND 6 years of relevant experience

Knowledge, skills, and abilities:

• Proficiency in programming languages such as Python, R, or Java.
• Ability to work independently and as part of a team while being collaborative in resolving problems 
• Excellent analytical and organizational skills
• Effective communication skills, both written and verbal.
• Ability to work collaboratively in a team environment.
• Basic understanding of molecular biology, genetics, or related life sciences disciplines.
• Strong analytical skills, with the ability to process and analyze biological data.
• Familiarity with bioinformatics tools and databases.

Education & experience:

• 2 or more years in a research position, including at least 1 year of supervisory and project management experience

Knowledge, skills, and abilities:

• Expertise in cancer biology
• Experience with machine learning and statistical data analysis.
• Familiarity with next-generation sequencing data analysis.
• Prior exposure to project management and cross-disciplinary collaboration.
• Demonstrated ability to learn new computational methods and tools rapidly.
• Interest in contributing to the development and optimization of bioinformatics pipelines.
•  

Apply online. Please be sure to upload a Cover Letter and Resume/CV.

We offer a variety of benefits on top of joining a thriving organization:

• Medical, dental and vision coverage at no or low cost to employees
  • Covered 100% for full-time employees and 88% for dependents
• Several retirement plans to choose from with contributions from OHSU
• 25 days a year of paid time off
• 8 days of sick time off
• Commuter subsidies
• Tuition reimbursement
• Access to group life insurance, disability insurance and other supplemental benefits
• Annual Merit Increase
• Growth/Development Opportunities
• Employee discounts to local and major businesses

#linkedin #indeed #knightcancerjobs #knightresearchandlabjobs #knightcompbiojobs

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.