Oregon Health & Science University

Senior Core Scientist

Job Locations US-OR-Portland
Requisition ID
2025-34657
Position Category
Research
Position Type
Regular Part-Time
Job Type
Research
Department
Department of Neurology
Salary Range
Commensurate with experience
FTE
0.20
Schedule
TBD
Hours
8 hours per week
HR Mission
School of Medicine
Drug Testable
No

Department Overview

OHSU is Oregon’s only public academic health center and an institution of higher learning, with schools of medicine, nursing, pharmacy, dentistry and public health. OHSU is also a national research hub, with thousands of scientists developing lifesaving therapies and deeper understanding of health and disease. Across the missions of healing, teaching and discovery, OHSU turns discoveries into lifesaving care.

The Advanced Light Microscope Core is the university-wide shared resource for OHSU researchers to access technical expertise in designing light microscopy projects and access to instrumentation and software to execute them. Services provided include technical consulting on sample preparation and instrument selection, assistance with image data acquisition, training for unsupervised instrument operation, and assistance with workflow development for data analysis.

Function/Duties of Position

From the General Core Scientist Descriptor Matrix:

GENERAL FOCUS:

The Core Scientist family provides technology expertise for researchers across campus. Core Scientists provide service functions in a core that, depending on the core, include service projects, assay services, or equipment training. Core management duties include responsibilities for service quality assurance and compliance, project and request tracking, financial duties around recharge mechanisms, and user outreach. Core leadership duties include operational and financial oversight, reporting, staff recruitment, training and mentoring, and staff and user management.

 

GENERAL SCOPE:

Oversees the design of core service functions, procedures, and day-to-day operations in support of customers' research goals and grant commitments. Monitors results, responds to unusual outcomes, and develops and implements modifications to address any technical or design issues.

 

Performs work of the highest difficulty using extensive knowledge of specialized technology. With expert knowledge of research practices and core technologies, directs and trains staff in methodology/Standard Operating Procedures.

 

Serves as a mentor to junior staff. Contributes to new service development. Assists with billing. May have responsibilities in developing fee and service cost estimates for projects and monitoring expenditure and income. May be tasked with operations compliance with applicable regulations. Trains users on advanced instrument use and verifies that proper training procedures are followed. Participates in user education webinars/seminars.

Required Qualifications

  • PhD AND 3 years’ relevant experience OR
  • Master’s Degree in relevant field AND 7 years’ relevant experience or core-relevant expertise OR
  • Bachelor’s in relevant field AND 15 years of relevant experience or core-relevant expertise

From the Advanced Light Microscopy Core Descriptor Matrix. Proficiency in lower level core scientist roles is assumed, plus this role periodically or regularly performs a majority of the following:

  • Understands multiphoton excitation principle and can train users in operating microscopes with multiphoton lasers.
  • Skilled in maintaining and troubleshooting most imaging systems in the core.
  • Can advise investigators on the relative merits of different modalities as they pertain to their imaging projects.
  • Can identify gaps and participates in development of new imaging services and training materials.
  • Assists in evaluation of new technologies and their development as new services. 
  • Demonstrated experience operating advanced ZEISS microscope setups run under the ZEN platform.

Preferred Qualifications

  • Demonstrated experience with quantitative data analysis of light microscopy data (publications).
  • Proficiency with open-source image data analysis software (e.g., FiJi/ImageJ, CellProfiler, QPath, or ilastik)
  • Proficiency with at least one commercial image data analysis packages (e.g., Arivis, Imaris, or Volocity).

All are welcome

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.

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