This project investigates the developmental specification and functional properties of "pioneer" neurons during cranial sensory circuit formation. The position builds on our recent work: https://pubmed.ncbi.nlm.nih.gov/40593691/. We are interested in following questions related to the pioneer neurons’ biology: how pioneer neurons are specified and migrate to their destination, how they interact with surrounding tissues, and what pioneer-specific factors guide follower neurons. 

• Performing experiments, including CRISPR based screen in the zebrafish model, generating mutant and transgenic zebrafish lines, fluorescent immunolabeling, fluorescent in situ hybridization, confocal imaging, generation of new CRISPR-based knock in lines as well as additional genetics and imaging experiments in the zebrafish model as needed. 

• Writing manuscripts and grants. 

• Ph.D. in relevant field

• 3 years of lab experience

• Basic knowledge of molecular biology and neuroscience, basic lab technique; relevant publications

• Ph.D. in molecular biology or related field

• 3-5 years of laboratory experience

Work is generally 40 hours per week during normal working hours, however, some evening and weekend work will be necessary on occasion. Additional safety training will be required to work with cell lines/ infectious bacteria or viruses/ working with in a BSL-2 environment. Use of dosimeter and adherence to radiological safety ordinances is required. Working with laboratory animals is required.

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.