The Brody lab is part of the Brenden-Colson Center for Pancreatic Care, which consists of multiple labs from various specialties and backgrounds committed to studying pancreatic cancer with the common goal of improving treatment for patients. The Brody lab works closely with the Dept. of Surgery and the Knight Cancer Institute at OHSU; it is a medium-sized, very active and highly collaborative lab focused on merging advanced molecular biology techniques, human and genetically engineered models, and translational medicine applications in order to tackle this fortuitous disease.

 

For this position, we are looking for an exceptional candidate who will contribute to ongoing research examining how several genes and molecular entities promote the onset, development, and survival of pancreatic cancer tumors. We are particularly interested in using new tools to interrogate the RNA-binding protein HuR (Human antigen R) and its regulation of critical pathways and molecules for cancer cell survival and proliferation.

The Brody lab routinely utilizes molecular biology and biochemistry techniques, mammalian tissue culture, small animal (mouse) models, imaging, and next generation –omics techniques (i.e. RNA-seq). The ideal candidate is expected to be proficient or willing to become proficient in these techniques, and to contribute their own independent ideas and skills to the growth of the lab. Applicants will need to possess strong organizational and communication skills as well as the ability to work independently, taking advantage of excellent facilities and scientific environment.

• Develop and implement research plan

• Analyze data 

• Prepare presentations and manuscripts, contribute to grant preparation 

• Contribute to general lab maintenance

• PhD in cell biology, molecular biology, biochemistry, or related field.
• Experience with molecular biology and protein characterization (i.e. Western blotting) techniques.
• Experience with cell culture.
• Comfortable with the use of mouse models.
• Must possess energy and drive to coordinate multiple tasks and projects simultaneously.
• Must have excellent communication, analytical and organizational skills: both written and verbal.
• Ability to work independently and as part of a team while being collaborative in resolving problems.
• Capable of analyzing data and writing up results into appropriate manuscript form.

• Experience with next-generation omics techniques (RNA-seq, proteomics, ATAC-seq).
• Experience with bioinformatics and/or statistical analysis is a plus.

Work schedule may vary depending on study requirements and project deadlines. Environmental exposures include working with lab reagents as well as human and animal tissues and blood samples.

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.