The Johnson lab within the department of Molecular Microbiology & Immunology (MMI) focuses on two human herpes viruses: herpes simplex virus (HSV) and human cytomegalovirus (HCMV). The lab studies interactions between these viruses and host cells, the immune system, and viral pathogenesis.
This position will assist in the investigation of how human cytomegalovirus infects and spreads in relevant human cell types with the focus on characterizing virus membrane glycoprotein function and interactions with host cell receptor molecules. The position will also involve performing virology based assays using a variety of mammalian cell lines in a tissue culture model system. Additional duties will include characterizing virus and host cell proteins by western blot, ELISA assays, immunofluorescent microscopy and other standard techniques. This position will also entail performing additional molecular biology techniques such as recombinant DNA technology, protein expression and purification, antibody production, and preparation of live viruses. Some lab management duties such as administration of IACUC protocols, general lab maintenance, ordering, and reagent preparation will also be required.
Work hours are Monday - Friday, 8:00am - 5:00pm, occasional weekends and evenings as needed. Work is performed in a laboratory setting that includes handling of infectious agents including viruses, hazardous chemicals and human samples.
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