This individual will be responsible for specific sections of ongoing and newly funded projects using non-human primates in the study of the immune system, immunodeficiencies, infectious diseases, and specific pathogen free non-human primate projects supported by infectious disease research laboratories and the Infectious Disease Resource in the Division of Pathobiology at ONPRC. They may have responsibility for overseeing labs or research units, collecting and processing animal tissues, training and supervising of research assistants (1 and 2), and preparation of written reports and, as applicable, regulatory documentation. They may assist with necropsies and sample collection and processing of terminal...

Isolate and culture cardiac myocytes and sympathetic neurons: Learn and perform protocols to culture sympathetic neurons, cardiac myocytes, and co-cultures for proximity labeling studies. Introduce DNA encoding the APEX-tagged SAP-97 construct into cultured myocytes for the proximity labeling studies. Work with the proteomics core to identify hits from the labeling.  Analysis of immune response: Carry out survival surgery in mice including implantation of minipumps. Assess physiological parameters including ECG and blood pressure. Isolate immune cells from hearts exposed to AngII hypertension (with and without drugs to promote nerve regeneration) and quantify immune cells by flow...

We are developing an exciting new type of cancer diagnostic test that combines microfluidic and microarray technology to pull cancer-derived nanoparticles straight from plasma. Our long-term goal is to bring nanoparticle-based diagnostics to the clinic for the first time. We are currently hiring for a highly motivated and enthusiastic Research Assistant 2 or Senior Research Assistant.   We are looking for applicants with expertise...

This is an NIH grant funded position with Dr. Stuart Ibsen. We are developing an exciting new type of cancer diagnostic test that combines microfluidic and microarray technology to pull cancer-derived nanoparticles straight from plasma. Our long-term goal is to bring nanoparticle-based diagnostics to the clinic for the first time. We are currently hiring for 1-2 highly motivated and enthusiastic researchers with expertise in Engineering or Biology to work in some of the following general areas:  

Device Development support: - Will assist theengineers and clinicians (PIs) in diabetes device validation testing.  This position will also assist the principal investigator with preparations for FDA applications Clinical Trial Coordination: - Screen, recruit, and consent participants for interventional and observational outpatient...

We are seeking a full-time Clinical Research Associate to serve as Project Director (PD) of a clinical research study in people with cancer, specifically cancer survivorship, treatment-related toxicities and rehabilitation strategies. The PD will work directly with the PI, Lab Manager, and Intervention Supervisor to execute all aspects of the clinical research, with particular oversight for recruitment and data collection. This person is responsible for day-to-day project management duties and will be responsible for overseeing elements of the project that may include: participant recruitment and retention, development of study recruitment materials and procedures, regulatory compliance, data quality...

As a Senior Research Assistant, you will be part of the Knight Precision Cancer Biofabrication Hub, which combines bioprinting and microfluidics methods and cancer biology to address complex problems in cancer research and treatment. We seek candidates with experience (Master's degree preferable) in Tissue Engineering, Biomaterials, Cell and Tissue Biofabrication, 3D printing and/or organs on-a-chip. General expertise on bioengineering, or a related field will be considered, and at least one year of industrial experience, preferably in 3D printing or biofabrication would be preferred. The ideal candidate will have demonstrated project management skills, including developing and...

- Contribute to the scientific direction and planning for a project within the lab.  - Perform research experiments and analyze results for project within the lab. - Maintain lab equipment and supplies.

The Department of Oral Rehabilitation & Biosciences is seeking a Research Assistant 2 with Bachelor's Degree (4 yr) with major courses in field of research OR Associate's (2 yr) and 3 years of relevant experience to begin immediately. The candidate will perform research in-line with the goals of the principal investigator, Stephanie Momeni, Ph.D, MBA, PMP. The research group is dynamic, vibrant, funded by the NIH/NIDCR, and leverages microbiology and bioinformatics to discover how the bacteria living in the human oral cavity impact health and disease. The position will provide the opportunity to conduct and present research, publish papers, build a scientific network, and collaborate with other research groups.  

1. Always promotes the mission of the Knight Cardiovascular Institute through our Professional Standards of timely Customer Service, Reliability, Productivity, Professionalism, Accuracy, Timeliness, Integrity, and Problem-Solving.   2. Responsible for the lifecycle of bio samples while in the CTU from collection to shipping. This includes but is not limited to: - Works in collaboration with study coordinator to maintain and file regulatory and study documents of all samples collected for various studies. - Keeps detailed accounting records of all samples processed, shipped, and stored. - Creates and maintains a database of all bio samples in cryostorage. - Processes samples...

- Staining multiplex IHC antibody panels on FFPE slides - Image and data curation, data cleaning and tracking of projects through the mIHC workflow - Maintain rigorous quality control standards, keeping careful record and working closely with other scientists to coordinate complex experiments and troubleshooting. - Assist in creating presentations by identifying key information and images to include - Work independently within...

- Research - Conduct experiments using in vitro assays and small animal models including: animal injury and exercise models, cell and tissue culture, molecular biology and protein assays, histology, fluorescence microscopy, and image processing. - Data Analysis & Recording - Generate data and perform quantitative analysis using the above techniques/protocols - Maintain detailed records of...

The successful candidate will serve as a project leader under the direction of Drs. Nicole Bowles and Steven Shea as part of the CPCP. The postdoctoral scholar will work on multiple projects examining the interconnection between cannabis use (or related products) and sleep/circadian rhythms.   Primary duties will include developing scientific ideas, writing grant applications and manuscripts, data collection and management, and supervision of research assistants. The successful candidate will be proficient in project management and independently monitoring study operations,...

- Animal experimentation: Work with researchers in managing the animal colony, taking measurements, harvesting tissues for experimentation, animal surgeries and necropsies. - Wet lab duties: Assist researchers with processing animal and human tissues/blood, labelling, organizing materials for experiment days. Basic to advanced cellular and molecular techniques. Basic to advanced immunologic methodologies with tissue specimens, tissue culture and relevant assays. Use of aseptic techniques and statistical applications (Prism/GraphPad). -

- Work on research experiments relating to the Cell Fusion project or Stem Cell investigations as assigned by Dr. Melissa Wong. These studies will include a variety of technical approaches including: cell culture, live-cell imaging, FACS and characterization of cell phenotypes, as well as murine intestinal stem cell analyses in tissue or cell culture. - Sample collection and processing. Interaction with clinical staff to facilitate identification and collection of samples. Possible consenting of patients onto IRB approved protocol. -

This position is full-time postdoctoral level (PhD in neuroscience or biophysics) in the von Gersdorff lab in the Vollum Institute. - Planning, executing, and analyzing experiments for independent research project(s) using electrophysiology, molecular, cellular, and live imaging and computational approaches in the retina and/or CNS. - Manuscript preparation for individual projects and assisting other lab members with manuscripts as needed. - Assisting the PI and other lab members with grant application (data acquisition, writing assistance,...