The Research Associate will be responsible for most of the planning, implementation, and data interpretation associated with their own research. Additionally, the successful candidate is expected to interact with graduate students and research assistants/technicians and be actively involved in their scientific supervision and in the general research directions of the lab (both technically and intellectually).
A critical aspect of this position is to establish and maintain collaborations by taking full advantage of the terrific network of labs offered within OHSU, including the Brenden Colson Center for Pancreatic Care, the Sears Lab, the Dept. of Surgery, as well as the Knight Cancer Institute. Duties include:
- Planning, implementation, and data interpretations associated with their research and grant writing
- Animal experiments – small animals
- Laboratory assays and data analysis
- Scientific supervision of graduate students
- Preparation of grants and manuscripts
- Establishment and maintenance of new and existing collaborations within OHSU and at other institutes
- Attendance at Department/Division/Lab applicable meetings
We are searching for either a Senior Clinical Research Assistant or a Clinical Research Assistant.
The duties of this position include assisting with patient-oriented clinical research for the Pediatric Nephrology Division in the Department of Pediatrics at OHSU. The applicant will assist in the planning, implementation, operation, and evaluation of all clinical aspects of clinical research projects.
The candidate is responsible for recruiting, screening, and consenting patients for clinical trials in either ambulatory or inpatient settings.
The candidate will be responsible for data collection, monitoring of source documents, report generation, meeting with sponsor’s monitors, continuous quality assessment, and application of protocol guidelines.
Senior Clinical Research Assistant:
The Senior Clinical Research Assistant will be independently responsible for assigned research studies and will interact with internal departments and external sponsor representatives as applicable.
The position will require clinical study coordination, including facilitating subject entry into research projects, follow-up visits, biological specimen handling, and case report form completion.
The individual will work collaboratively with other study coordinators, nursing, pharmacy, specialty service centers, and physician staff in the care, scheduling, and management of research subjects. The Senior Clinical Research Assistant is independently responsible for regulatory compliance and IRB submissions related to assigned studies. The Senior Clinical Research Assistant will assist with preparing study budgets and work with the contracting team from study start-up to study closure. The Senior Clinical Research Assistant will assist in the supervision and professional development of Research Assistants, interns, volunteers, and students. The Senior Research Assistant will assist with scholarly activities, such as data analysis, grant, abstract, and manuscript development, and research results dissemination
Clinical Research Assistant 2:
Under general supervision, the Clinical Research Assistant 2 will manage their assigned research studies and will interact with internal departments and external sponsor’s representatives as applicable.
The position will require clinical study coordination, including facilitating subject entry into research projects, follow-up visits, biological specimen handling, and case report form completion. The Clinical Research Assistant 2 will initiate and assist with regulatory work, IRB submissions, and assist with preparing study budgets. The Clinical Research Assistant 2 will assist in the professional development of Research Assistants 1, volunteers, and students. The individual will work collaboratively with other study coordinators, nursing, pharmacy, specialty service centers, and physician staff in the care, scheduling, and management of research subjects.
As a Radiation Therapist you will administer radiation therapy accurately as prescribed and planned by a physician, and reinforce the Radiation Oncologist's advice to patients regarding reactions to treatment and their care. This position will require you to observe the clinical progress of the radiation oncology patient, use clinical decision-making skills to recognize and report any signs of complications, unusual reactions, and events to the nursing staff and/or Radiation Oncologist. Additional duties could include assisting with the training, mentoring, and/or directly supervision of Radiation Therapy students.
The successful candidate for this position will have demonstrated experience working as a Radiation Therapist. This includes the ability to safely and effectively operate a variety of computerized simulation and treatment machines, and the ability to perform all necessary machine and treatment quality assurances, and be able and willing to work in all areas within the unit. This position requires professional conduct and the ability to effectively communicate and interact within clinical settings with a variety of individuals in written and oral formats.
Experiments will include reprogramming PBMCs to iPSCs and characterizing the generated iPSCs for many different patient samples harboring different genetic mutations.
Manage the sequencing equipment in the Stem Cell Center.
Support the general functions of our Stem Cell Center which include ordering supplies, communications with collaborators, maintaining equipment and regulatory paperwork.
We are currently hiring for highly motivated postdoctoral fellows to join Dr. Thuy Ngo’s lab. The goal of Dr. Ngo’s lab is to develop and deploy technologies for analyzing cfRNA, cfDNA, extracellular vesicles (EV) and protein complexes in body fluids for applications in precisiondiagnosis and selection of therapy. Ngo lab also seeks to understand the complex environment of molecular features detected in body fluids associated disease progression and the evolution of diseases in response to treatment. Furthermore, the lab is investigating the basic mechanism of EV medicated cell-cell communication, EV's content packaging and delivery. Candidates would work in the following areas.
- Cell-free RNA and cell-free DNA methylation – Design experiments and perform sample preparation to sequence circulating RNA (mRNA, miRNA, transposable elements, circular RNA and microbiome) and DNA methylation from patient’s blood samples. Use existing tools and develop new methods to identify biomarkers, perform classification and prediction modelling, and analyze biological pathways associated with patient samples during cancer progression and under treatment.
- Extracellular vesicles- Design experiments and perform sample preparation to analyze protein and RNA cargos of extracellular vesicles in body fluids and spent culture media. Investigate mechanism of EV biogenesis and delivery.
- Developing new technologies for screening and measuring with low background, high sensitivity, high resolution and wide dynamic range to profile proteins and RNA cargos of EV and protein complexes, to characterize them physically and to measure them at both single complex level and at high a throughput manner.
- Transcriptome/Epigenome–Modeling and analyzing next-generation sequencing datasets that measure the transcriptome and the epigenome of cell-free RNA, cell-free DNA and extracellular vesicles in blood. Performing analysis of existing genomics data of cancerous cells to aid the design of cell-free RNA and cell-free DNA methylation assays. The successful candidate will use both existing tools and develop their own computational methods to analyze such datasets for characterization of healthy and cancerous patient populations.
- Machine Learning/Statistics/Multiomics – Developing machine learning methods and statistical models for feature selection, classification, anomaly detection, time series analysis, and multiomics data integration.
A Postdoctoral position in Cell, Cancer or Molecular Biology is available at the Knight Cancer Institute's Center for Experimental Therapeutics (CET). Interested candidates are expected to have recently obtained their PhD and have a strong track record of publications in Cell, Cancer or Molecular biology. Job duties include performing research to understand the role of newly identified drivers in the pathogenesis of cancer so as to identify novel therapeutic targets. The translational research projects within CET leverage multi-disciplinary approach in biology, chemistry, pharmacology, molecular modeling, in vitro and patient-derived models to probe complex biological processes and to pursue new therapeutic opportunities for various diseases. As a member of multi-disciplinary team, the postdoctoral candidate will receive training in various aspects of drug discovery & development for his/her career development.
- Perform hands-on experiments (in vitro and in vivo) and analyze/interpret data on assigned projects
- Critically evaluate relevant scientific advances and integrate this knowledge into research programs. Participate in project planning and execution
- Publish research in peer-reviewed journals and present work at scientific conferences. Effectively write and/or communicate research and regulatory materials. Attend and present at the project and group meetings and national conferences
As a Computational Biologist, Entry level, you will be a part of collaborative project teams to understand how individual genetic profiles influence risk of cancer development and progression. Specific projects include the Healthy Oregon Project (HOP), which is building a healthy population research repository, and understanding the impact of race on the evolution of mutations in cancer patients. Specific tasks include working with wet-lab researchers to refine methods and protocols to meet project needs, raw data processing, mutation calling, and identification of mutation signatures utilizing existing methods. Additional tasks include metadata cleaning and curation, participation in regular team meetings, publications, and grants.
Data Organization and Management
- Clean and manage metadata
- Access, store, and document raw data
- Coordinate with project team members
- Meet publication requirements, including data and code repositing
- Sample/sequencing quality control assessment
- Implement existing analytic packages and workflows
- Adapt existing resources as needed to meet project needs
- Develop novel analyses and visualizations
- Present at regular team meetings
- Clear code documentation
- Support manuscript preparation
- Support grant writing efforts
The position will be responsible of a single-cell proteomics platform (Cyclic-immunofluorescence). The position will be responsible for developing the experimental plan, scanning samples with a fluorescent microscope and analyzing data obtained through the Cyclic-Immunofluorescence platform. Position will use pre-established protocols and analysis pipeline and will contribute to the development and expansion of the platform. The successful candidate will employ sound experimental design and problem solving to create workflow that produces robust analyses, as well as collaborate with collaborators to deliver product meeting project objectives.
The position will also be responsible for analyzing results of reverse phase protein array (RPPA) assays to generate data reports. The position will use a pre-established analysis pipeline and will contribute to the development of analysis pipeline and standardized data report output.
The position may also help coordinate the schedules of shared microscope resources at OHSU. Experience with antibody-based assays and imaging techniques (immunofluorescence or immunohistochemistry) and single-cell analysis is preferable. Experience with imaging analysis, python, MATLAB and/or R is required.
Range minimum: $47,903/year. Starting salary will be determined based on education, experience, and internal equity at the time of offer
As a Computational Biologist, Entry level, you will be a part of collaborative project teams to understand how individual genetic profiles influence risk of cancer development and progression. Specific projects may include the Healthy Oregon Project (HOP), which is building a healthy population research repository, and understanding the impact of race on the evolution of mutations in cancer patients. Specific tasks include working with wet-lab researchers to refine methods and workflows to meet project needs, raw data processing, mutation calling, and identification of mutation signatures utilizing existing methods. Additional tasks include metadata cleaning and curation, participation in regular team meetings, publications, and grants.
- Data Organization and Management
- Data Analysis
- Technical Writing/Communication
- General CEDAR support
We are currently hiring for 1-2 highly motivated fellows with expertise in Computational Biology to work in the following areas. Candidate would work with CEDAR and OHSU scientists including Gurkan Yardimci, Hisham Mohammed, Andrew Adey, Srivathsan Ranganathan, and Xiaolin Nan initially and with increasing collaborations over time:
- Machine Learning/Statistics– Developing machine learning methods and/or statistical models to study the organization of the epigenome and three dimensional structure of the genome using cutting edge genomics and super resolution microscopy datasets. Developed algorithms will be used to deeply characterize cell populations and identify features that are indicative of cell state. Techniques such as (but not limited to) dimensionality reduction, clustering, and predictive modeling will be utilized.
- Genomics/single cell genomics Modeling and analyzing next-generation sequencing datasets that measure the transcriptome and the epigenome, with an emphasis on the single-cell variants, such as single cell RNA-seq and single cell ATAC-seq. The successful candidate will use both existing tools and develop their own computational methods to analyze such datasets for characterization of healthy and cancerous cell populations.
- Multiomics– Developing computational methods for the analysis of single-cell multiomics technologies that are able to characterize multiple “omes” of a single cell concurrently, such as the epigenome and the transcriptome (see references below). These methods will be utilized for deep characterization of healthy and cancerous cells and investigate the links between the transcriptome, the epigenome and 3D conformation of chromatin.
- Imaging – Performing analysis of existing genomics data of cancerous cells to aid the design of super high resolution microscopy experiments for imaging the chromatin organization of cancerous cells. The successful candidate will have the opportunity to analyze cutting edge super high resolution microscopy experiments and develop computational methods for joint analysis of genomics and imaging data.
- Molecular Modeling - Performing 3D structural modeling of proteins, nucleic acids and small molecules towards predicting biomolecular structure and interactions using MD simulations, molecular docking, and free-energy calculations. Implement AI/machine learning approaches to predict atomic level structures and interactions of proteins using Alphafold, RosettaFold etc.
- Prepare manuscripts, and present research findings as abstracts or oral presentations (travel may be required)
- Attend weekly group meetings and 1:1 meetings to: 1) present data and interpretation of results; 2) troubleshoot research results and 3) suggest next steps
- Attend research related meetings including but not limited to Thursday PM SPORE seminars, Cancer Biology meetings, journal clubs
- Perform experiments utilizing appropriate lab or computational techniques with proficiency, evaluate results, and determine the next steps to complete project and present data. Think independently and problem solve. Stay on top of the literature and build skills to maximize the projects’ potential.
- Duties as assigned
- Provide medical and advanced practice management independently and/or in conjunction with attending physicians. Works in conjunction with attending physicians to provide continued clinical care in the inpatient and outpatient settings.
- Communicate with attending physicians, patients and families regarding patients’ conditions, treatment plans, and urgent medical needs.
- Assure appropriate setting of care (inpatient, critical care, acute care).
- Document subjective and objective findings, assessment and plan clearly and accurately in daily progress notes.
- Identify discharge needs early and communicate plan to patients, families, nurse case manager, and other healthcare team members.
- Work with nurses, social workers, nutrition services, pharmacy and others as needed to assure optimum patient care.
- Make appropriate referrals to specialty care service within OHSU and outside of OHSU.
- Consult with specialty care providers when appropriate.
- Maintain communication with external providers and other individuals and agencies (e.g. skilled nursing facilities) as appropriate.
- Perform clinical procedures as indicated (e.g. central venous access, chest drains, intubation).
- Adheres to best practice protocols and policies.
- Respond to and manage adverse infusion reactions and other emergencies, and review patient labs and physical conditions in order to override treatment parameters as appropriate.
- Ordering as needed (PRN) medications.
- Review urgent EKG’s, imaging, laboratory studies and other ancillary tests prior to start of treatment.
- Review investigational study EKG’s, imaging, labs and other ancillary tests prior to start of treatment.
- Provide consultation to OTU nurses.
- Consult with pharmacists on treatment changes and PRN medications.
Quality and Research:
- Work with clinic and hospital staff to optimize order sets, patient instructions, and other infrastructure that supports patient care.
- Identify and engage in opportunities to improve the quality and efficiency of care provided to trauma patients.
- Promote use of appropriate research findings in practice to exceed the standards of care.
- Work with the physician leadership, nurse managers, nursing staff and social workers to prevent and/or respond to patient complaints.
- Effectively manage resources.
- Participate as coinvestigator in clinical research studies.
Clinical Activities (not related to teaching or research):
- Plans and supervises student lab and/or clinical experiences or practice based on teaching assignments.
Scholarly Activities (research/writing, abstracts, grant-supported work, presentations, etc.):
- Engages in professional activities related to interest and expertise and participates in scholarly productivity that meets the school’s promotion and tenure requirements by faculty rank.
- Faculty in the practice mission demonstrate competence in an area of clinical expertise and engage in inquiry and scholarship that contributes to the practice of clinical practice.
- Faculty in the research mission advance a program of research, prepares grants and seek funding, and engage with other missions to foster inquiry within the SON.
Education Activities (include types of teaching and types of students taught):
- Provides effective didactic instruction based on teaching assignments using appropriate instructional technologies to ensure that course outcomes are met.
- Participates in curriculum development, assessment, and revision, and the development of student learning outcomes as requested by Program Administrators.
- In partnership with the Program Director, Assistant Program Director, and other faculty, acts to ensure integration of program didactic and clinical curriculum.
- Assists with student orientation, advisement, evaluation, and assessment of remediation needs of students as requested by Program Administrators.
- Faculty in the doctoral program supervise students in dissertation and/or clinical inquiry projects.
- These activities could include faculty meetings, committee membership, professional activities, and other responsibilities as assigned by the Program or Academic Director.
- Participates in faculty governance; additional engagement based on rank.
- Documents activities for the purpose of accreditation maintenance.
- As negotiated.
- Maintains continuous self-development in teaching and clinical skills; performs self-evaluation and goal setting yearly.
- Follows appropriate University, School, and Program procedures in the management of student affairs.
- The appointee shall provide services as assigned by the supervisor in furtherance of the university’s missions and goals of teaching, research, patient care, outreach, and public service.
The Information Technologies Group (ITG) supports OHSU’s mission by developing, implementing and maintaining technology-based services and solutions.As part of the Information and Collaboration Services team, the student worker will assist with technical documentation, the IT departmental newsletter, website maintenance, operational and project communications, and the administration of the campus IT services user group. Materials developed will support systems changes or downtimes, new technologies, upgrades and security notifications. This position will work with a cross-functional team of communications, training and customer service professionals. ITG is happy to partner with students who wish to receive credit through their degree program for this work. Students are expected to work 10-15 hours per week during regular office hours, Monday – Friday, 7:30 a.m. – 5:30 p.m., with a set schedule for each term. ITG’s core hours are 10 a.m. – 3 p.m. The position is available for 3-4 quarters (9-12 months). This is a full remote, teleworking position.
The Information Technologies Group (ITG) supports OHSU’s mission by developing, implementing and maintaining technology-based services and solutions. As part of the Information and Collaboration Services team, the student worker will assist with technical documentation, the IT departmental newsletter, website maintenance, operational and project communications, and the administration of the campus IT services user group. Materials developed will support systems changes or downtimes, new technologies, upgrades and security notifications. This position will work with a cross-functional team of communications, training and customer service professionals. ITG is happy to partner with students who wish to receive credit through their degree program for this work.
As a member of the Department of Molecular and Medical Genetics the Clinical Geneticist will report to the Department Chair, and will be responsible for duties in the areas outlined. This position will pursue and execute scholarly and service activities including instruction, clinical practice, community service and administrative duties for the department; instruct medical, dental, nursing, graduate students, and house staff; engage in scholarly research activities directed towards the understanding, detection, and treatment of disease; serve on School and OHSU committees as approved by the Chair; engage in such public service as will benefit the community and the University; and serve in such administrative functions as may be assigned by the Chair.
- Provides quality real time 2D, 3D, M Mode and doppler applications to acquire images with accuracy and efficiency, using optimal skills and knowledge of equipment.
- Documents and demonstrates knowledge and skill to evaluate normal /abnormal anatomy and any related pathologies for presentation to Radiologist.
- Demonstrates knowledge and skill in ultrasound physics.
- Exercises responsible judgment in recognizing and reporting significant situations relating to patient care.
- Performs portable procedures when needed.
- Prepares and instructs the patient for the diagnostic study using age appropriate communication skills.
- Optimizes each image during the examination to obtain the highest quality study with the least discomfort to the patient.
- Must be able to perform all ranges of exams after completion of technical competencies.
- Assists the physician in invasive and/or specialized procedures, such as amniocentesis, needle biopsy, localizations, and tumor masses, as directed.
- Continues to stay current in regards to new US technology hardware and software upgrades.
- Verifies complete documentation of all pertinent information to provide accurate and timely service to customers.
- Verifies and initials orders in patient chart, Responsible for correctly identify patients by complying with Imaging dept. Patient Identification Policy.
- Labels images completely with patient demographics, position or other required documentation.
- Follows through with all aspects of scanning duties in order to provide efficient and timely completion of examinations with correct data entry, begin and complete with correct billing and verification that images are in PACS.
PERSONAL & PATIENT CARE & SAFETY
- Provides for personal and patient care and safety using professional judgement in accordance with written standards to avoid injury to self and others.
- Responsible to adhere to all established JCAHO National Patient Safety Goals, and report errors or unsafe conditions to supervisor and the OHSU Event Reporting (Patient Safety Net).
- Follows universal precautions for blood and body fluids, protecting patients and staff.
- Works in a safe manner by maintaining a clean work environment.
- Identifies and reports any issues for ergonomic improvement to supervisor.
Reports injuries to supervisor.
Hiring Bonus and Relocation Package Available
The OHSU Clinical registered nurse (RN) provides compassionate, evidence-based, and efficient care to individuals, families, communities and patient populations. The Clinical RN's care delivery is consistent with the Oregon Nurse Practice Act, the ANA Scope and Standards of Practice, and the ANA Code of Ethics. The Clinical RN demonstrates the professional role obligations of scientist, leader, and knowledge transferor [Onsomble Model of the Professional Role™]. Professional accountability enriches the Clinical RN's engagement as a leader in promoting an inter-professional culture of collaborative decision-making, innovation, life-long learning, and teamwork. The Clinical RN exemplifies the principles of a Culture of Safety by committing to a Just Culture, a Reporting Culture, a Learning Culture, and an Engaged Informed Culture.
- Assist with the admitting and discharge
- Obtain accurate vital signs and weight
- Complete all unit specific CNA documentation in the patient’s medical record related to: admissions, daily care, vital signs, weight, intake and output, discharge, etc.
- Assist the patient with any and all basic hygiene, lifting, transport, dietary support, and other personal needs and medical necessities
- Support patient and family centered care
- Report potential compliance problems as outlined in the Code of Conduct
- Model ethical and appropriate behavior, professional standards, compliance, and personal integrity
- Must be able to perform the essential functions of the position with or without accommodation
Join our team as an adult cardiac sonographer. In this role you will be a vital member of our team, working collaboratively with health care providers to provide direct and indirect care to patients undergoing procedures in the Cardiac Non Invasive Services Department and throughout the hospital. In this position, you will work autonomously and in partnership with OHSU team members to perform transthoracic echocardiograms, stress echocardiograms, and transesophageal echocardiograms. This position includes rotational evening and weekend call. As a member of our team, you will receive the opportunity to contribute to the best patient outcomes and we will provide you the opportunity to grow within the highly specialized cardiovascular division. Grow your career with us!
1. Documentation and Charges
Collects all appropriate collateral documentation for client, doctor, etc. and ensures all required signatures are collected. Completes all required notes and documentation in Epic for all services provided that meets expectations of OAR 309-019-0140 Service Plan and Service Notes. Completes appropriate Epic charge entry related to services delivered. Works with PAS Resource Specialist on required insurance authorization documentation as necessary or required.
2. Culturally Competent Care and Interpretation
Provides culturally competent care and linguistic/interpretation services for specific client population. Provides linguistic/interpretation services during co-facilitated patient/doctor visits. Ensures that client needs are appropriately addressed serving as interpreter/facilitator for both patient and doctor. Assists medical provider and administrative staff in scheduling subsequent doctor visits.
3. Patient Referrals and Intakes
Triages inquiries from potential clients, family members and/or service providers regarding scope of treatment and services provided by IPP. Collaborates with medical providers in reviewing cases and scheduling clients for psychiatric evaluations and follow-up. Adhering to OAR 309-019-0135
4. Assessment and Treatment Planning
Conducts mental health assessment and annual mental health assessment updates, and develops and revises treatment plans. Adhering to OAR 309-019-0135; 309-019-0140.
5. Case Management
Assists in coordinating client care with other providers. Assists patients in gaining access to community services. Responds appropriately to patient needs related to mental health treatment, including need for urgent therapeutic interventions. Conducts outreach home visits as necessary.
6. Individual, Group and Family Services
Conducts individual, group and family therapy using evidence-based interventions. Conducts individual and group skills training and related services.
7. Clinic Operations
Assists with general clinic operations, including scheduling of transportation for clients, responding to language-specific telephone inquiries, and other appropriate duties as needed.
8. Staff Meetings and Development
Attends and actively participates in required staff meetings, development activities, and utilization review. Attends required supervision sessions with designated supervisor.
9. Prevention, Education and Outreach
Conducts prevention, education, and outreach activities as specified in county contracts to serve OHP members.
10. Research/Grant Activities
May provide limited assistance to medical staff in performing research/grant specific to the activities carried out in the Intercultural Psychiatric Program.