This position is primarily responsible for implementing and supporting database-driven web applications and automation tools to support the operations of the Knight Diagnostic Laboratory and Knight Biolibrary with a focus on application configuration, customization and queries. The incumbant will develop, support, and enhance existing and new research, laboratory, and administration systems through elucidation, analysis and understanding of user requirements, businesses processes, and system functionality.  Duties to perform include elucidating, developing, and translating system requirements into a technical design; implementing that design; producing software documentation to support the entire software development life cycle; developing application interfaces and system integrations; developing and conducting ETL processes; writing software tests; troubleshooting existing software; supporting software upgrades and maintaining disaster recovery documentation for the systems.  This position will focus and serve the needs of the Knight Cancer Institute including the Knight Diagnostic Laboratories and Knight Biolibrary.

The Senior Clinical Research Assistant has the primary responsibility of coordinating a multi-site implementation trial focused on testing a patient-centered hypertension decision support tool called COACH. This includes supporting recruited and enrolled patients as they participate in the trial, preparing progress reports and study materials, overseeing instructions for participants, coordinating advisory group meetings, IRB management, and other administrative tasks. Tasks also include performing extensive reviews of existing hypertension guidelines and protocols, assisting with manuscript and conference submissions, working with health team members and hypertension patients to understand their goals, experiences, and motivation, and facilitation of this large implementation trial to test the COACH app with various stakeholders.

- General Accounting/Month End - assist with the month-end and annual financial closing processes, including preparation and input of journal entries, preparation of supporting schedules and in-depth analysis of account balances. Responsible for the reconciliation of asset valuation and liability reconciliations on a monthly basis, including cash and fund balance accounts. A thorough understanding of GAAP (Generally Accepted Accounting Principles) is required in order to analyze account balances, investigate transactions to resolve questionable data, and to book appropriate correcting entries as necessary. Prepares monthly Foundation intercompany reconciliation as well as monthly elimination information needed for day’s cash calculation and the consolidating of Foundation financials into OHSU financials. Develop a thorough understanding of the accounting validation rules, OHSU accounting policies, and fiscal authority structure in the Oracle general ledger module. - Responsible for monitoring monthly balance sheet reconciliations. This includes maintaining the master reconciliation file, updating the Bridge site each month with listing of reconciliations due and responsible parties, sending out notices of due dates, and following up with  delinquent reconcilers. This requires tact, persistence, and the ability to educate others in proper reconciliation procedures. - Reviews balance sheet reconciliations prepared by others to ensure accurate and relevant information is provided. Work with preparers on proper reconciliation processes when needed, including training new employees and assisting others on new accounts. - Be a backup resource for certain Internal Billing System/Fiscal Authority processes, such as Role Requests, No Holders, and Incomplete FAIDS. This requires knowledge of OHSU Fiscal Authority policies, as well as Oracle processes. - Perform other duties and/or projects as assigned by the Manger. Projects will involve interpreting and analyzing accounting data which requires a thorough understanding of GAAP.

As a Senior Research Assistant, you will be part of collaborative CEDAR project teams focusing on advancing early cancer detection. You will support CEDAR research by assisting in research activities of CEDAR projects where needed and as appropriate for your training and interest. You will help to design and implement experiments and will have independent responsibility for research studies. You will conduct research with minimal supervision. You will have a detailed knowledge of all aspects of laboratory research and need to be comfortable working both individually and in highly collaborative teams. You should possess good organizational and interpersonal skills. You will contribute to the scientific direction and planning for projects within CEDAR. Major roles for you will involve providing support and working directly in projects involving animal work, cellular and molecular biology experiments, assisting in experimental design, training scientists and supervising students and Research Assistants, maintaining laboratory space and supplies, assisting in various other research activities, and organizing samples, datasets and studies.

The non-OHSU student worker will receive training in procedures common to a biohazard immunology research lab, and assist the lab with paperwork, organizing, cleaning, data analysis, simple laboratory tasks.  As competency is demonstrated with basic skills, the worker will be given progressively more challenging assignments, including cell isolation from clinical specimens, and the creation of fluorescently-stained samples for flow cytometry or simple computational/database analyses. - Willingness to work with pathogens potentially dangerous to humans - Willingness to work in Biosafety Level 2 and 3 facilities - Willingness and ability to work flexible hours - Ability and willingness to work independently - Ability to carry and lift 35 lbs. - Ability to stand for three continuous hours a day - Ability to work on computer for five continuous hours a day - Able to perform the essential functions of the position with or without accommodation

- Write computer programs in Python - Use software for numerical optimization of high-dimensional functions - Assign biophysical models based on likelihood optimization for experimental data

An exciting opportunity has been created for an experienced researcher to join Dr. Olga Nikolova’s group as a Computational Biologist I at Oregon Health & Science University in Portland, OR. Dr. Nikolova’s research program is focused on predictive models for cancer biology, with a special interest in leukemia.   Duties will include computational analysis of genomic bulk and single-cell data in both single modalities and multi-omes, including RNAseq, ATACseq, CITE-seq, CyTOF, and custom assays developed in-house. Applicant will establish and maintain pipelines and participate in data analysis and visualization. The applicant will develop new tools and methods for analyzing emerging data types and adapt statistical methods to assess the robustness of new tools. The applicant will be able to independently interact with wet-lab biologists to analyze data and guide the analysis strategy. Will be responsible for the deposition of sequencing data and published algorithms. Will work with other investigators to enable their use of algorithms developed by the team. Will participate in the writing of grants and manuscripts. Applicants will need to possess strong organizational and communication skills and the ability to work collaboratively.   Experience with R, Python, and Bash/Unix is required. Salary will be commensurate with experience. We are looking for an enthusiastic individual who is capable and willing to make maximum use of excellent facilities and a productive environment.

- Bioinformatics analysis - Cell culture - Flow cytometry analysis

- Primary Research (including planning, granting, execution, analysis, publication)  - Maintain laboratory compliance documentation for human, animal, biological and radiological work. - Be familiar with lab safety infrastructure and ensure compliance with all safety regulations. - Interact with biosafety, chemical safety, and safety officers on behalf of the Principal Investigator.  - Generate data and research analysis for investigator's use in preparation of technical reports and publications. - Assist the PI with manuscript preparation and grant applications. - Present, or assist in the presentation of, research projects at retreats, seminars, conferences and other OHSU or public venues.  - Providing training to users on lab practices and protocols, including sample preparation and instrumentation use.  - Maintain an accurate and detailed laboratory notebook of all experiments performed. Participate in lab meeting.  - Training of lab personnel and supervision of Research Assistants, students and other lab members.  - Perform routine lab operations, including but not limited to the purchase of laboratory supplies, monitoring supplies and maintaining all laboratory equipment.  - Other responsibilities as assigned by the supervisor in furtherance of the lab’s research and the university’s missions and goals of teaching, research, patient care, outreach and public service. 

Plumbing Activities— Assist in the installation of new plumbing including pipes, drains tubs, faucets, and other plumbing fixtures and equipment; make simple repairs on old plumbing such as renewing washers and valves and repairing sinks; clean and open drains and toilets, and other water lines. Basic plumbing knowledge a must. Corrective and Preventative Maintenance of building equipment— Maintain, troubleshoot, and repair building systems including pumps, fans, compressors, and vacuum systems. Lubricate equipment, change belts and filters as needed. Must be able to trace a building system line. Facility Maintenance and Repairs— Perform facility maintenance relating to building electrical, plumbing, doors, windows, roofs, fire equipment, ceiling tiles, flooring and carpet. Includes lamp replacement and the use of heavy-duty augers and sewer cleaning equipment to unplug blocked drains, sinks, and toilets. Perform small office modification jobs for customers, including mounting whiteboards, hanging art, installing keyboard trays, etc. Basic knowledge of carpentry and tools necessary; also, rudimentary understanding of construction principles and basic mechanical knowledge. Professional Development and Training — Requires continuous learning and development of technical skills and knowledge to keep pace with changes in technology. Review technical journals and relevant literature and the attendance of training as often as needed to keep knowledge current. Provide technical leadership to other Facility Management staff; instruct less experienced employees as they assist with maintenance to help them develop their skills and provide a progressive work environment; includes providing limited direction to employees in the Facilities Technician 1 classification. Administrative Duties— Attend all required meetings and training classes and sucessfully complete any proficiency evaluation (verbal or written ) which may be required to demonstrate adequate comprehension. These evaluations may also be administered to satisfy the requirements of OSHA, JCAHO, and other agencies upon which OHSU depends for accreditation. Functional Duties— Accurately complete all paperwork as required (dailylabor reports, job plans, work orders, etc.) and turn in all paperwork in time. Maintain cleanliness and orderliness of immediate work area and maintain security of personal hand tools, common shop tools, supplies, and vehicles. Perform emergency duties or other duties as assigned by the Associate Vice President of Facilities and Real Estate or designee. Customer Service— Assumes role as primary customer service representative for all Facilities & Logistics operations and services on assigned Work Orders, responding to both internal and external customers in a timely, effective, and professional manner, developing positive working relationships. Other Duties— Assist in the repair of small plant or specialty equipment. Fabricate tools, machinery and machine parts from metal, wood, plastic, and sheet metal using some machine tools and other forming tools and equipment. This may include forging, tempering, straightening, bending and welding iron and steel, and soldering or brazing other non-ferrous metals.

Hiring Bonus up to $10,000 DOE and Relocation Package Available. Must begin work by July 1, 2024 to qualify   The Assistant Nurse Manager (ANM) is a registered nurse (RN) who is responsible for upholding excellence in the provision of nursing care through the implementation of the Profession Practice Model. The ANM, in association with the Nurse Manager, is responsible for the managerial and leadership functions within a patient environment. The ANM partners with the interdisciplinary care team to ensure the delivery of safe, quality patient care and compliance with regulatory standards, and administrative and clinical policies and procedures. The ANM performs managerial activities, and demonstrates effective leadership behaviors including performing evaluations, employee mentoring, coaching, and performance management. The ANM implements quality and safety initiatives, engages in process improvement, ensures adherence to bargaining unit agreements and human resource management. The ANM creates and sustains a patient care environment that supports a safe, knowledgeable, compassionate, productive, and engaged staff.    The ANM’s decisions and actions are based on ethical principles as outlined by the American Nurses Association. The ANM practices in adherence with the American Nurses Association’s (ANA) Nursing Administration: Scope and Standards of Practice for Nurse Administrators, the ANA Code of Ethics, the Oregon State Board Nurse Practice Act, and within the context of the Nurse Executive Competencies developed by the American Organization of Nurse Executives (AONE). The ANM exemplifies the principles of the OHSU Culture of Safety Position Statement by committing to a Just Culture, a Reporting Culture, a Learning Culture, and an Engaged Informed Culture.   Benefits   OHSU offers competitive, affordable benefits that include health care, income protection and more. See highlights below or learn more about OHSU benefits. - Comprehensive health care plans. Covered 100% for full-time employees and 88% for dependents for .9 FTE and higher. - $25K of term life insurance provided at no cost to the employee - Two separate above market pension plans to choose from - Paid time off- 208 hours per year (full-time), prorated for part-time - Extended illness bank- 64 hours per year, prorated for part-time - 9 paid holidays per year - Three weeks of paid parental leave - Adoption assistance program (up to 5k) - Substantial Tri-met and C-Tran discounts - Tuition Reimbursement - Innovative Employee Assistance Program (EAP)

Hiring Bonus and Relocation Package Available -Must start by July 1, 2024 to qualify   Are you an experienced Emergency Department RN who enjoys being involved in projects that make a difference for other nurses? Do you like to solve problems? Have you been told that you are a natural leader? Do you communicate well in a crisis?  If you answered YES to any of these questions, we have just the job for you. The Emergency Department Assistant nurse manager is a frontline leader who engages with emergency department staff to improve the work environment.  Assisted by a dynamic team of leaders who work well together, have great senses of humor and who truly care about the staff they work with, you will improve the care environment.   We work at a Magnet Designated Level One Trauma Center, Cardiac Center of Excellence and Comprehensive Stroke Center.  We care for the sickest patients in the state and we do it well. The leadership goals of this department include a focus on staff safety and decreasing workplace violence, reducing capacity challenges, improving clinical outcomes and improving staff engagement including rewards and recognition.   A successful Assistant Nurse Manager will be motivated, a good communicator, and will bring ideas to improve the work environment. Why wait, join this dynamic team now! - The Assistant Nurse Manager (ANM) is a clinical leader who works closely with the Nurse Manager and the Adult Assistant Nurse Manager to support the employees and services of the Emergency Department.  They also work closely with the Director of Nursing to align unit goals with the strategic plan. - The Assistant Nurse Manager prioritizes visibility in the Emergency Department and the support of evening and or night shift. - This is the perfect position for a clinical nurse who desires the next step in taking a formal leadership role.  - ANMs are mentored in leadership and perform essential leadership functions such as employee evaluation, mentoring, coaching and performance management.  - The ANM implements quality and safety initiatives, engages in process improvement, ensures adherence to bargaining unit agreements and human resource management. The ANM creates and sustains a patient care environment that supports a safe, knowledgeable, compassionate, productive, and engaged staff. - Works cooperatively and supportively with the heads of diagnostic and therapeutic departments to ensure availability, quality, and effective use of support services to support Emergency Department throughput - Maintains clinical competency in Emergency Services in order to provide occasional nursing responsibilities to support Emergency Department daily operations. - Collaborates with EMS to maintain evidence based standards of care and optimize department flow. - Participates in investigations regarding lost or misplaced patient property. - Responsible for operational, quality, human resources, financial, strategic and clinical management of the Emergency Department under the direction of the Emergency Department Nurse Manager. - Must be able to deal with competing needs and priorities of internal and external customers including ensuring safe conditions for patients, families and staff. - Exercises the ability to implement a flexible schedule to meet operational needs and to create work-life balance. The ANM’s decisions and actions are based on ethical principles as outlined by the American Nurses Association. The ANM practices in adherence with the American Nurses Association’s (ANA) Nursing Administration: Scope and Standards of Practicefor Nurse Administrators, the ANA Code of Ethics, the Oregon State Board Nurse Practice Act, and within the context of the Nurse Executive Competencies developed by the American Organization of Nurse Executives (AONE). The ANM exemplifies the principles of the OHSU Culture of Safety Position Statement by committing to a Just Culture, a Reporting Culture, a Learning Culture, and an Engaged Informed Culture.  

Surgery Scheduler Maintains current information regarding surgery schedules for service site providers. Serves as liaison and information resource for physicians, nursing support staff, coworkers, IP Admitting Department, Surgery Office, and Periop Services. Collects from physician all information necessary to schedule a surgery (including ICD9 codes, equipment needs, etc.). Maintains surgery information to OR as soon as received. Starts insurance process and obtains authorizations. Facilitates care arrangements by scheduling preops, PAT clinic, ancillary and clinical services as needed. Applies problem solving and negotiating skills in resolving provider and patient concerns and other surgery related problems.    Telecommunications Triages and documents accurately telephone calls from patients including requests for medication refills, complaints, general information inquiries, and urgent health care concerns. Delivers such information or requests promptly to the appropriate providers or their designees.    Arranged Care Schedules new patient appointments on line, and manually if necessary. Obtains prior medical records and studies if appropriate. Creates a medical records if needed. Arranges stretchers, wheelchairs, and interpreters when necessary, and accommodates other special needs whenever possible. Mails information packets. Provides personal reminders to patients about upcoming appointments. Obtains and prepares OHSU medical records before scheduled appointments.    Provides high quality customer service to both external customers (patient, referring providers, and insurance carriers) and internal customers (OHSU health care providers and staff) that meets or exceeds the service standards of the health care industry. This duty includes prompt and professional communication efforts, face -to-face customer contact skills, crisis management, facility with available information, technology, standard complaint processing, flexible coverage of internal service needs, and the continuous application of process improvement methods and skills.    Administrative Support for Assigned Surgeon – scheduling meetings, managing calendar, legal correspondence, appeal letters, coordinating travel, projects, and other duties as assigned. 

Partnerships  - Partner with SON leaders to execute plans and projects to achieve goals under the OHSU 30-30-30 initiative. - Partner with School of Nursing Senior Performance Improvement Consultant (Sr. PIC) and SON leadership to identify and prioritize strategy deployment opportunities, strategic initiatives that have transitioned to operations and other operational improvement projects (policies, processes and procedures). Includes coverage planning for strategy deployment related meetings and activities. - Gather information and perspectives via multiple channels from SON leadership, faculty, staff, students and other stakeholders regarding opportunities and needs for improvement and/or change, and summarize and present feedback and recommendations for programs, projects and initiatives. - Establish and maintain relationships with appropriate leaders and other stakeholders, providing regular communication on project statuses and changes, including reporting project outcomes and/or risks to the appropriate stakeholders — escalating issues as necessary based on program or project work plans. Program and Project Management - Provides comprehensive project management expertise in assigned strategic objectives including transitioning to operations initiatives and other operational improvement projects; partners with SON Sr. PIC, managers, management teams, and key stakeholders on projects as part of the strategic deployment process. - Collaborate with assigned strategic and or transition to operations workgroups, establish, document and track the scope of projects, project team composition, roles, tasks, funding estimations and status, and timelines. Assists the workgroups with developing, identifying, assigning, and prioritizing tasks related to the project. - Utilizes project management tools to facilitate project success by meeting project timelines within scope. Assists team members with meeting their deadlines and accomplishing tasks when needed. - Develops strong customer relationships and works to comprehend and document customer needs and SON program capabilities. - Assists with connecting with appropriate SON staff when needed – e.g. the finance team to advise on feasibility/cost-benefit evaluation of proposed solutions. - Helps process owners effectively communicate relevant information to stakeholders by setting up tracking systems and structures for reporting (e.g. dashboards). - Works with project team to help with their comprehension and the implementation of PM methodology. - Set and manage stakeholder and project team expectations, ensuring projects align with School of Nursing strategic goals. - Identify, coordinate and communicate the interrelatedness of various projects to create synergy, efficiency, and minimalize duplication of efforts, within the School of Nursing and across OHSU. - Collaborate with process owners, creating long- and short-term project plans, including setting targets for milestones and adhering to deadlines. - Monitor and track the progress of multiple projects, analyzing the successful completion of project milestones, and when necessary, adapt scope, and timelines to ensure that project team adheres to project requirements. - Establish and maintain processes to manage scope over the project lifecycle, setting project quality and performance standards across multiple projects. - Ensure relevant OHSU standards, processes and policies are followed throughout project and program implementation. - Analyze, evaluate and overcome program and project risks, and communicate risks through program reports to leaders and stakeholders. - Create and maintain comprehensive project documentation including spreadsheets, diagrams and job aids; measure project performance using appropriate project management tools.

This is an NIH grant funded position with Dr. Stuart Ibsen. We are developing an exciting new type of cancer diagnostic test that combines microfluidic and microarray technology to pull cancer-derived nanoparticles straight from plasma. Our long-term goal is to bring nanoparticle-based diagnostics to the clinic for the first time. We are currently hiring for 1-2 highly motivated and enthusiastic researchers with expertise in Engineering or Biology to work in some of the following general areas:   - Development of biological particle separation techniques using dielectrophoresis technology – using microelectrode array chips to recover cancer-derived nanoparticles from circulation (Gustafson, et al. 2021). This novel work will focus on the development and characterization of new nanoparticle recovery techniques using dielectrophoretic forces. These forces are created by microelectrode array devices that act on the unique dielectric properties of different particles (Ibsen et al. 2017). This work includes increasing particle collection efficiency, understanding the types of particles that are collected and how they can be separated, and developing an internal standard appropriate for different particle types. This position will utilize the high-end specialized dielectrophoresis equipment located here at OHSU. This will also involve quantitative fluorescent microscopy imaging, TEM imaging, immunostaining, and particle characterization. - System automation– continuing development and finalization of an automated system to conduct the dielectrophoresis work. The goal is to automate the dielectrophoresis collection protocol to increase sample analysis throughput. This will involve basic robotics and automation programming in LabView. - Cancer biomarker panel development– evaluate the nanoparticle associated biomarkers that are collected for their ability to detect pancreatic cancer from plasma samples. Here the goal is to use the developed dielectrophoresis techniques to collect cancer-derived nanoparticles and evaluate their biomarkers for the ability to detect pancreatic cancer.   Selected References: - Luna, Ramona; Heineck, Daniel; Hinestrosa, Juan Pablo; Dobrovolskaia, Irina; Hamilton, Sean; Malakian, Anna; Gustafson, Kyle T.; Huynh, Katherine T.; Kim, Sejung; Ware, Jason; Stimson, Ella; Ross, Christian; Schutt, Carolyn E.; Ibsen, Stuart. “Enhancement of Dielectrophoresis-Based Particle Collection from High Conducting Fluids Due to Partial Electrode Insulation.” Electrophoresis, In Press (2023) - Hamilton, Sean; Shea, Delaney; Ibsen, Stuart*, Brasino, Michael*. "On‐chip dielectrophoretic recovery and detection of a lactate sensing probiotic from model human saliva." Electrophoresis, Volume 44, Issue 3-4: pp. 442-449. (2023) *Co-corresponding authors - Luna, Ramona; Heineck, Daniel P.; Bucher, Elmar; Heiser, Laura; Ibsen, Stuart. "Theoretical and Experimental Analysis of Negative Dielectrophoresis Induced Particle Trajectories." Electrophoresis, Volume 43, Issue 12: pp. 1366-77 (2022) (Cover) - Gustafson, Kyle; Huynh, Katherine; Heineck, Daniel; Bueno, Jesus; Modestino, Augusta; Kim, Sejung; Gower, Austin; Armstrong, Randall; Schutt, Carolyn; Ibsen, Stuart. “Automated Fluorescence Quantification of Extracellular Vesicles Collected from Blood Plasma using Dielectrophoresis.” Lab on a Chip, Volume 21, Issue 7: pp. 1318-1332. (2021) (Back Cover) - Sarno, Benjamin; Heineck, Daniel; Heller Michael J.; Ibsen, Stuart. “Dielectrophoresis: Developments and Applications from 2010 to 2020.” Electrophoresis, Volume 42, Number 5, pp. 539-564 (2021). (Cover) - Ibsen, Stuart; Wright, Jennifer; Lewis, Jean; Kim, Sejung; Ko, Seo-Yeon; Ong, Jiye; Manouchehri, Sareh; Vyas, Ankit; Akers, Johnny; Chen, Clark; Carter, Bob; Esener, Sadik; Heller, Michael."Rapid isolation and detection of exosomes and associated biomarkers from plasma." ACS Nano, Volume 11, Issue 7, pp. 6641-6651 (2017).

An exciting opportunity has been created for an experienced researcher to join the Dr. Anupriya Agarwal  Laboratory at the OHSU Knight Cancer Institute as an Senior Research Associate in Portland, OR to study the mechanisms of leukemia initiation and drug resistance using multi-omics approaches.   Dr. Agarwal and her team for over past 15 years focusing on identifying novel signaling pathways that are requisite for leukemia initiation, clonal evolution, and drug resistance.  This position will be a hybrid between wet lab and computational disciplines, with a dedicated mentorship in both areas. The new team member will help lead the project focused on understanding the mechanisms of leukemia initiation and drug resistance in a context dependent manner.  The project will use variety of advanced molecular biology techniques, CRISPR methods along with single cell transcriptomic, epigenetic, and genomic profiling in premalignant and malignant models using murine and human cells in vitro and in vivo. The candidate should also be able to perform complex data analysis, along with downstream analyses using computational approaches. Applicants will need to possess strong technical and organizational skills as well as the ability to manage an independent project.   A PhD and 1-2 years of post-graduate research experience in the relevant field is preferred. Laboratory and/or computational experience in the field of molecular/cellular biology, cancer biology or a related field is preferred. Experience with sequencing library preparation, epigenetics, flow cytometry, or murine models of disease would be especially beneficial. The ideal candidate would have deep expertise in a singular area of focus but may also have worked as boundary spanners across multiple fields. Salary will be commensurate with experience. Achieving this position requires that the researcher have demonstrated a satisfactory track record of scholarly activity including high-quality peer-reviewed publications. We are looking for an enthusiastic individual who is capable and willing to make maximum use of excellent facilities and a productive environment.   Relevant publications for the position are below: - Yang F, Long N, Anekpuritanang T, Bottomly D, Savage JC, Lee T, Solis-Ruiz J, Borate U, Wilmot B, Tognon C, Bock AM, Pollyea DA, Radhakrishnan S, Radhakrishnan S, Patel P, Collins RH, Tantravahi S, Deininger MW, Fan G, Druker B, Shinde U, Tyner JW, Press RD, McWeeney S, Agarwal A*. Identification and prioritization of myeloid malignancy germline variants in a large cohort of adult AML patients. Blood. 2022, 139(8): 1208-1221 PMC9211447, *Corresponding author. Prospective in ASH Clinical News, Selected for Podcast and Commentary in Blood 2022. - Kurtz S, Eide CA, Kaempf A, Long N, Bottomly D, Nikolova O, Druker BJ, McWeeney SK, Tyner JW, Agarwal A.Associating Ex Vivo Drug Sensitivity with Differentiation Status Identifies Effective Drug Combinations for Acute Myeloid Leukemia. Blood Advances 2022, 6(10): 3062-3067. - Hosseini MH, Kurtz SE, Abdelhamed S, Mahmood S, Davare, MA, Kaempf A, Elferich J, McDermott JE, Liu T, Payne SH, Shinde U, Rodland KD, Mori M, Druker BJ, Singer JK, Agarwal A. Inhibition of interleukin-1 receptor-associated kinase-1 is a therapeutic strategy for acute myeloid leukemia subtypes. Leukemia. 2018, 32(11):2374-87. PMC6558520 - Carey A, Edwards D, Eide C A, Newell L, Traer E, Medeiros B, Pollyea DA, Deininger MW, Collins R, Tyner J W, Druker B J, Bagby G C, McWeeney S, Agarwal A*. Identification of interleukin-1 by functional screening as a key mediator of cellular expansion and disease progression in acute myeloid leukemia. Cell Reports. 2017, 18(13):3204-18. PMC5437102 - Agarwal A, Bolosky BJ, Wilson DB, Eide CA, Olson SB, Fan G, Druker BJ. Differentiation of leukemic blasts is not completely blocked in acute myeloid leukemia. Proc Natl Acad Sci U S A. 2019, 116(49):24593-24599. PMC690050. * Co-corresponding Author- Highlighted in “In This Issue PNAS”. - Bottomly D, Long N, Schultz AR, Kurtz SE, Tognon CE, Johnson K, Abel M, Agarwal A……. et al; Integrative Analysis of Drug Response and Clinical Outcome in Acute Myeloid Leukemia. Cancer Cell 2022, in press (collaborative manuscript)

We are seeking a highly motivated, detail-oriented Research Project Coordinator, Entry to support CEDAR’s Specimen and Data Repository by coordinating the collection and banking of biological samples and data. These samples and the associated data will be a resource for researchers within CEDAR to support the innovation of new early detection technologies.   In this role you will work closely with the Research Project Coordinator for the CEDAR Specimen and Data Repository to ensure regulatory compliance, manage researcher requests for samples and data, and ensure efficient operations with our clinical collaborators.  This position also requires cross training in all repository responsibilities including, but not limited to, clear and timely communication with researchers and clinic staff, transport of clinical samples, and proper processing and storage of multiple sample types. This position also involves patient medical chart review, clinical data accessing, annotation, and querying using the laboratory information management system(s).   Required skills include – strong documentation skills and attention to detail, the ability to design, implement, and follow repository protocols with limited supervision to ensure that all samples are collected and stored in an appropriate and consistent manner with proper data input and safeguards.  Phlebotomy certification is required to train repository staff and assure work on venipuncture, and to enable you to serve as back-up when additional effort for blood draws are needed.

Clinical: The fellow will be responsible for attending specified joint clinic(s) with the supervising faculty. The fellow will also conduct independent general clinic(s). The fellow will also be responsible for attending a weekend inpatient consult service on a rotating basis.   Research: The fellow will function integrally in the research activities of the Department as determined by the Fellowship Director. The fellow will be responsible for on clinical research project culminating in presentation at a state or national meeting.   Teaching: the fellow will function integrally in the teaching activities of the Department as determined by the fellowship director.

The Phlebotomist collects blood, urine, stool, and sputum specimens from pediatric and adult patients, as ordered by healthcare providers, for use in performing diagnostic or prognostic tests and provides related clerical, transporting and non-technical support to the laboratory.   Specimen Collection: - Uses Hospital/Laboratory Information System(s) to access orders and check for completeness and accuracy of orders; determines the proper method to collect specimen(s) based on tests to be performed and selects correct tubes, needles or other necessary supplies to collect specimen(s); locates patient and verifies patient identification using at least two patient identifiers; prepares collection site; utilizes a variety of techniques to collect blood specimens from patient by venipuncture, finger stick, or heel stick and/or instructs patient on the proper collection for urine, stool or sputum; checks condition of patient for fainting or bleeding; bandages venipuncture site; labels all specimen(s) with correct labels and prepares specimen(s) for delivery to appropriate laboratory; enters collection information (time, date, collector, and method of collection) into Laboratory Information System, and defers and/or cancels uncollected specimen requests. Clerical and Customer Service Responsibilities: - Greets patients; reviews and reconciles orders for patient encounter; enters off-hill orders; telephones physicians and clinics to clarify orders and arrange specimen re-draws; answers telephones and provides information to callers; interacts with laboratories, medical staff, and patients to resolve problems associated with specimen collection; maintains customer service focus at all times; endeavors to make patients comfortable; meets needs of patients, even if extra effort is required; communicates professionally by phone and in person, with patients, nurses, providers, and staff. Training Duties: - Provides instruction to new employees, hospital staff, and students/externs on correct techniques for collecting specimens from patients; observes, monitors, and evaluates trainees’ progress. Specimen Transport: - Prepares specimens for transportation to and from laboratory sites; maintains specimen integrity by storing and transporting appropriately.  Miscellaneous Tasks: - Ensures adequate supply levels; discards expired supplies; maintains cleanliness in area where specimen(s) are collected; utilizes safety protection equipment and disposes of used supplies in correct containers; observes safety and infection control policies; may order stocks and supplies for work area; participates in unit meetings and training programs.

Operational Leadership - Drive operational performance initiatives. Direct the analysis and create the understanding off key operational and financial outcomes including: ALOS, case mix, ambulatory utilization, cost per case, inpatient volumes etc., to recognize trends, evaluate status, and in concert with physicians make decisions and organize interventions - Provides leadership in the coordination of service line meetings, working with clinical leaders, medical directors and members to develop agendas. - Partners with others to enhance healthcare and, ultimately patient care through interdisciplinary activities, such as education, consultation, management, technological development, or research opportunities - Applies systems theory with an understanding that how parts of a system relate to the overall system - Leads and practices patient/family advocacy and promotes patient-centered decisions and outcomes - Maintains visibility and open communication with the staff and department leadership - Communicates plans and decisions to department staff and other stakeholders - Ensures the care environment supports the provision of safe quality care, and a work place that promotes shared decision-making, accountability, autonomy and engagement - Reflects on own method of decision-making and the role of beliefs, values and inferences to develop leadership and performance capacity - Practices within shared-governance structures to distribute leadership and promote decision-making appropriate level within the governance structure - Celebrates successes and accomplishments Performance Improvement - Develops the service line quality plan in collaboration with Quality Management department and organizational leaders - Oversees all regulatory activity associated with Hospital accreditation and program certifications - Drives clinical performance initiatives. Review, monitor, and analyze monthly and quarterly reports to recognize trends, evaluate status, and in concert with physician co-leaders, makes decisions and organize interventions - Evaluates the practice environment and designs and implements quality improvement strategies to ensure nursing sensitive outcomes meets or exceeds established goals - Evaluates the impact/benefits of system, organizational, nursing, and department initiatives - Supports workflow processes that builds a culture of safety - Uses current research findings and other evidence to expand clinical knowledge, enhance role performance, and increase knowledge of professional issues Service Line Direction & Strategic Planning - Achieves performance objectives and influences decision making and action through matrix relationships - Under the guidance of OHSU Health Heart and Vascular Service Line executive sponsors, and in collaboration with the Strategy department, Medical and Surgical Directors, partner to define strategic business focus, i.e. growth, maintenance or curtailment of activities as appropriate, using integrated information about customer(s), market(s) and competitors to recognize and recommend initiatives that align with OHSU Strategic Plan - Work with Strategy department and OHSU Health System Partners on strategic vision and operational planning in relationship to cardiovascular programs across the health system - Builds and manages relationships with outside organizations that are beneficial in executing service line business and strategy, including those that add value to OHSU’s reputation at the regional and national level. - Collaborates with other OHSU affiliates and health systems on an as-needed basis to grow and support cardiovascular services within the state and regionally - Partners on the development of tactics to achieve goals and strategies. Direct the execution of tactics to meet or exceed performance objectives of Heart and Vascular Service Line - Recognizes linkages to institutional initiatives and incorporate those implications when solving problems and making decisions - Actively participate in physician recruitment and retention strategies - Identify capital funding required to support strategic initiatives and work with peers to prioritize and approve submissions - Collaborate with outside partners as business and clinical opportunities may arise Financial Management - Evaluates service line leaders’ achievement toward financial performance targets - Develops innovative solutions and applies strategies to obtain appropriate resources for nursing - Promotes activities that inform others about cost, risks, and benefits or care, or of the plan and solution. Professionalism - Promotes translation of theory, scope & standards into practice to exercise autonomy and decision-making authority at the leadership level - Advances practice excellence by communicating a clear and consistent message about the ownership of role and standards -based professional practice - Mentors and supports others to access resources for their professional development - Engages in informal and formal processes of giving and seeking feedback regarding role performance from individuals, professional colleagues, representatives, administrators, and others